2. Signaling Pathways
  3. GPCR/G Protein
    Neuronal Signaling
  4. Cannabinoid Receptor
  5. CB1 Isoform
  6. CB1 Antagonist

CB1 Antagonist

CB1 Antagonists (16):

Cat. No. Product Name Effect Purity
  • HY-14137
    Rimonabant Hydrochloride
    		Antagonist 99.95%
    Rimonabant Hydrochloride (SR 141716A Hydrochloride) is a highly potent and selective central cannabinoid receptor (CB1) antagonist with an Ki of 1.8 nM.
  • HY-18697
    JD-5037
    		Antagonist 98.05%
    JD-5037 is a potent CB1R antagonist with an IC50 of 1.5 nM.
  • HY-112340
    TM38837
    		Antagonist 99.00%
    TM38837 is a peripheral selective cannabinoid receptor type 1 (CB1) receptor antagonist.
  • HY-13505
    AM281
    		Antagonist ≥99.0%
    AM281 is a selective CB1 receptor antagonist with an IC50 of 9.91 nM.
  • HY-14136
    Rimonabant
    		Antagonist
    Rimonabant (SR141716) is a highly potent, brain penetrated and selective central cannabinoid receptor (CB1) antagonist with a Ki of 1.8 nM.
  • HY-141411A
    Zevaquenabant
    		Antagonist
    Zevaquenabant ((S)-MRI-1867) is a peripherally restricted, orally bioavailable dual cannabinoid CB1 receptor and inducible NOS (iNOS) antagonist.
  • HY-110179
    PSNCBAM-1
    		Antagonist
    PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM.
  • HY-121616
    (R)-SLV 319
    		Antagonist
    (R)-SLV 319 is a potent and selective cannabinoid receptor 1 (CB1) antagonist with a Ki value of 894 nM.
  • HY-W011040
    LY320135
    		Antagonist
    LY320135 is a potent and selective antagonist of CB1 receptor, with a Ki of 141 nM.
  • HY-133533
    O-2050
    		Antagonist
    O-2050 is a high affinity cannabinoid CB1 receptor antagonist with a Ki of 2.5 nM.
  • HY-103336
    Tocrifluor 1117
    		Antagonist
    Tocrifluor 1117 (T1117), a fluorescent form of the cannabinoid CB1 receptor antagonist AM251 (HY-15443), is a selective fluorescent GPR55 ligand.
  • HY-14788
    Drinabant
    		Antagonist
    Drinabant (AVE1625) is an orally active CB1 receptor antagonist.
  • HY-110020
    rel-O-2050
    		Antagonist
    rel-O-2050 (Compound O-2050) is a neutral cannabinoid CB1 receptor antagonist.
  • HY-14791
    Ibipinabant
    		Antagonist
    Ibipinabant (SLV319) is a potent, selective and orally active antagonist of cannabinoid CB1 receptor, with a Ki of 7.8 nM.
  • HY-103326
    NIDA-41020
    		Antagonist
    NIDA-41020 is a potent and selective cannabinoid receptor 1(CB1) antagonist with a Ki of 4.1 nM.
  • HY-103327
    MJ15
    		Antagonist
    MJ15 is a potent and selective CB1 receptor antagonist with a Ki of 27.2 pM and an IC50 of 118.9 pM for rat CB1 receptors.