2. GPCR/G Protein Neuronal Signaling
  3. Cannabinoid Receptor
  4. PSNCBAM-1

PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity.

For research use only. We do not sell to patients.

PSNCBAM-1 Chemical Structure

PSNCBAM-1 Chemical Structure

CAS No. : 877202-74-9

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5 mg USD 140 In-stock
10 mg USD 220 In-stock
25 mg USD 375 In-stock
50 mg USD 560 In-stock
100 mg USD 795 In-stock
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Based on 1 publication(s) in Google Scholar

PSNCBAM-1 Related Antibodies

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Description

PSNCBAM-1 is a selective CB1 receptor allosteric antagonist with an EC50 of 0.1 μM. PSNCBAM-1 can be used in the researches of obesity[1].

IC50 & Target

hCB1-R

0.1 μM (EC50)

Molecular Weight

392.88

Formula

C22H21ClN4O
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

ClC(C=C1)=CC=C1NC(NC2=CC=CC(C3=CC=CC(N4CCCC4)=N3)=C2)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (318.16 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.5453 mL 12.7265 mL 25.4531 mL
5 mM 0.5091 mL 2.5453 mL 5.0906 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.5453 mL 12.7265 mL 25.4531 mL 63.6327 mL
5 mM 0.5091 mL 2.5453 mL 5.0906 mL 12.7265 mL
10 mM 0.2545 mL 1.2727 mL 2.5453 mL 6.3633 mL
15 mM 0.1697 mL 0.8484 mL 1.6969 mL 4.2422 mL
20 mM 0.1273 mL 0.6363 mL 1.2727 mL 3.1816 mL
25 mM 0.1018 mL 0.5091 mL 1.0181 mL 2.5453 mL
30 mM 0.0848 mL 0.4242 mL 0.8484 mL 2.1211 mL
40 mM 0.0636 mL 0.3182 mL 0.6363 mL 1.5908 mL
50 mM 0.0509 mL 0.2545 mL 0.5091 mL 1.2727 mL
60 mM 0.0424 mL 0.2121 mL 0.4242 mL 1.0605 mL
80 mM 0.0318 mL 0.1591 mL 0.3182 mL 0.7954 mL
100 mM 0.0255 mL 0.1273 mL 0.2545 mL 0.6363 mL
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PSNCBAM-1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

PSNCBAM-1877202-74-9PSNCBAM1PSNCBAM 1Cannabinoid ReceptorInhibitorinhibitorinhibit

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