Insulin Receptor Inhibitor
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AG1024 (Standard)
0 ImagesCat. No.: HY-10253RCAS No.: 65678-07-1Synonyms: Tyrphostin AG 1024 (Standard)AG1024 (Standard) is the analytical standard of AG1024 (HY-10253). This product is intended for research and analytical applications. AG1024 (Tyrphostin AG 1024) is a reversible, competitive and selective IGF-1R inhibitor with an IC50 of 7 μM. AG1024 inhibits phosphorylation of IR (IC50=57 μM). AG1024 induces apoptosis and has anti-cancer activity.
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NVP-ADW742 (Standard)
0 ImagesCat. No.: HY-10252RCAS No.: 475488-23-4Synonyms: ADW742 (Standard); GSK 552602A (Standard); ADW (Standard)NVP-ADW742 (Standard) is the analytical standard of NVP-ADW742 (HY-10252). This product is intended for research and analytical applications. NVP-ADW742 (ADW742) is an orally active, selective IGF-1R tyrosine kinase inhibitor with an IC50 of 0.17 μM. NVP-ADW742 inhibits insulin receptor (InsR) with an IC50 of 2.8 μM. NVP-ADW742 induces pleiotropic antiproliferative/proapoptotic biologic sequelae in tumor cells.
