Isotope-Labeled Compounds
Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time.
MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.
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Isotope-Labeled Compounds Related Products (11098)
Related Products (11098)
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Thiamethoxam-d3
0 ImagesThiamethoxam-d3 is the deuterium labeled Thiamethoxam. Thiamethoxam is a broad spectrum neonicotinoid insecticide.
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8-Hydroxy amoxapine-d8
0 ImagesCat. No.: HY-12389SCAS No.: 1189505-24-58-Hydroxy amoxapine-d8 is the deuterium labeled 8-Hydroxy amoxapine.
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Higenamine-d4-1 hydrochloride
0 ImagesCat. No.: HY-N2037AS1Synonyms: Norcoclaurine-d4-1 hydrochloride; Demethyl-Coclaurine-d4-1 hydrochlorideHigenamine-d4-1 (Norcoclaurine-d4-1) hydrochloride is deuterium labeled Higenamine (hydrochloride). Higenamine hydrochloride is a selective LSD1 inhibitor (IC50=1.47 μM) that can be isolated from aconite. Higenamine hydrochloride has anti-inflammatory and antibacterial activity. Higenamine (Norcoclaurine) can attenuate IL-1β-induced Apoptosis through ROS-mediated PI3K/Akt signaling pathway. Higenamine hydrochloride protects brain cells from oxygen deprivation. Higenamine can promote bone formation in osteoporosis through the SMAD2/3 pathway. Higenamine hydrochloride can be used to study cancer, inflammation, cardiorenal syndrome and other diseases.
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Thioridazine 2-Sulfone-d3
0 ImagesCat. No.: HY-B0965SCAS No.: 1329652-09-6Thioridazine-d3 2-Sulfone is the deuterium labeled Thioridazine hydrochloride. Thioridazine hydrochloride, an orally active antagonist of the dopamine receptor D2 family proteins, exhibits potent anti-psychotic and anti-anxiety activities. Thioridazine hydrochloride is also a potent inhibitor of PI3K-Akt-mTOR signaling pathways with anti-angiogenic effect. Thioridazine hydrochloride shows antiproliferative and apoptosis induction effects in various types of cancer cells, with specificity on targeting cancer stem cells (CSCs).
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Hydroxy Itraconazole-d6
0 ImagesCat. No.: HY-12772S3Synonyms: R-63373-d6Hydroxy Itraconazole-d6 (R-63373-d6) is deuterium labeled Hydroxy Itraconazole. Hydroxy Itraconazole (Itraconazole metabolite Hydroxy Itraconazole; R-63373) is an active metabolite of Itraconazole (ITZ), which is a triazole antifungal agent.
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Ethyl methanesulfonate-d5
0 ImagesEthyl methanesulfonate-d5 is the deuterium labeled Ethyl methanesulfonate.
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Betamethasone 17-propionate-d5
0 ImagesCat. No.: HY-142196SBetamethasone 17-propionate-d5 is the deuterium labeled Betamethasone 17-propionate.
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Dihydromyricetin-d4
0 ImagesCat. No.: HY-N0112SSynonyms: Ampelopsin-d4; Ampeloptin-d4Dihydromyricetin-d4 (Ampelopsin-d4) is deuterium labeled Dihydromyricetin. Dihydromyricetin is a potent inhibitor with an IC50 of 48 μM on dihydropyrimidinase. Dihydromyricetin can activate autophagy through inhibiting mTOR signaling. Dihydromyricetin suppresses the formation of mTOR complexes (mTORC1/2). Dihydromyricetin is also a potent influenza RNA-dependent RNA polymerase inhibitor with an IC50 of 22 μM.
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Cytidine-d13
0 ImagesCat. No.: HY-B0158S8Synonyms: Cytosine β-D-riboside-d13; Cytosine-1-β-D-ribofuranoside-d13Cytidine-d13 (Cytosine β-D-riboside-d13) is deuterium labeled Cytidine (HY-B0158). Cytidine is a pyrimidine nucleoside and acts as a component of RNA. Cytidine is a precursor of uridine. Cytidine controls neuronal-glial glutamate cycling, affecting cerebral phospholipid metabolism, catecholamine synthesis, and mitochondrial function.
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Sesamin-d8
0 ImagesCat. No.: HY-N0121SCAS No.: 3047060-14-7
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Tristearin-13C3
0 ImagesCat. No.: HY-127035S1CAS No.: 287100-84-9Synonyms: Glycerol tristearate-13C3Tristearin-13C3 (Glycerol tristearate-13C3) is 13C labeled Tristearin. Tristearin is a triglyceride derived from three units of stearic acid.
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Bictegravir-d5
0 ImagesCat. No.: HY-17605S1Synonyms: GS-9883-d5Bictegravir-d5 is deuterated labeled Bictegravir (HY-17605). Bictegravir (GS-9883) is a potent inhibitor of HIV-1 integrase with an IC50 of 7.5 nM.
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5-Methoxyuridine-d3
0 ImagesCat. No.: HY-112581S5-Methoxyuridine-d3 is the deuterium labeled 5-Methoxyuridine (HY-112581). 5-Methoxyuridine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc.
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AALQEELQLC-(Lys-13C6,15N2) TFA
0 ImagesCat. No.: HY-P11527SAALQEELQLC-(Lys-13C6,15N2) TFA is the 13C- and 15N-labeled AALQEELQLC.
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N10-Monodesmethyl Rizatriptan-d3
0 ImagesCat. No.: HY-132432SCAS No.: 1215678-02-6N10-Monodesmethyl Rizatriptan-d3 is the deuterium labeled N10-Monodesmethyl Rizatriptan.
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Carbimazole-d3
0 ImagesCat. No.: HY-W744953Carbimazole-d3 is deuterium labeled Carbimazole. Carbimazole is an orally active antithyroid agent which rapidly converts to Methimazole after absorption and prevents thyroid peroxidase enzyme from iodinating and coupling the tyrosine residues on thyroglobulin, hence reducing the production of thyroxine. Carbimazole also displays anti-inflammatory and neuronal-protective activities, suggesting its application for hyperthyroidism and neurological research.
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Myristic acid-13C2
0 ImagesCat. No.: HY-N2041S8CAS No.: 287111-20-0Myristic acid-13C2 is the 13C-labeled Myristic acid (HY-N2041). Myristic acid is an orally active saturated 14-carbon fatty acid found in most animal and plant fats, especially milk fat coconut oil, palm oil and nutmeg oil. Myristic acid exerts anti-inflammatory activity through the NF-κB pathway. Myristic acid has antibacterial, anti-inflammatory and analgesic properties.
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11-cis-Retinoic Acid-d5
0 ImagesCat. No.: HY-14649S211-cis-Retinoic Acid-d5 is the deuterium labeled Retinoic acid. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha[1][2].
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Pyrimidifen-d4
0 ImagesCat. No.: HY-W703863SPyrimidifen-d4 is the deuterium labeled Pyrimidifen (HY-W703863). Pyrimidifen is a phenoxyethyl amine compound and is an acaricide. Pyrimidifen controls the African red mite, Eutetranychus africanus with a persistency of 14-21 days.
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Azathioprine-d3
0 ImagesCat. No.: HY-B0256SCAS No.: 2702733-53-5Synonyms: BW 57-322-d3Azathioprine-d3 (BW 57-322-d3) is the deuterium labeled Azathioprine (HY-B0256). Azathioprine (BW 57-322) is an orally active immunosuppressive agent. Azathioprine can be converted in vivo to the active metabolite 6-mercaptopurine (6-MP). Azathioprine has myelosuppressive effects and induces apoptosis.
