Parasite
Antiparasitics are a class of medications which are indicated for the treatment of parasitic diseases such as nematodes, cestodes, trematodes, and infectious protozoa.
Parasite Isoform Specific Products
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Parasite Produits associés (2481)
Produits associés (2481)
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Related Compound Screening Libraries (1)
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Parasite Isoform Comparison
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Tetrandrine (Standard)
0 ImagesSynonyms: NSC-77037 (Standard); d-Tetrandrine (Standard)Tetrandrine (Standard) is the analytical standard of Tetrandrine. This product is intended for research and analytical applications. Tetrandrine (NSC-77037; d-Tetrandrine) is a bis-benzyl-isoquinoline alkaloid, which inhibits voltage-gated Ca2+ current (ICa) and Ca2+-activated K+ current.
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Hexythiazox-d11
0 ImagesCat. No.: HY-B1851SCAS No.: 2714418-33-2Hexythiazox-d11 is deuterium labeled Hexythiazox. Hexythiazox is a selective acaricide with ovicidal, larvicidal and nymphicidal activities. Hexythiazox is widely used for chemical control of mites on cotton, fruits and vegetables. Hexythiazox is harmless to mammals and has no effect on beneficial insects and predators of mites.
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Methyl Clonazepam-d3
0 ImagesCat. No.: HY-W740297CAS No.: 1189992-73-1Methyl Clonazepam-d3 is the deuterium labeled Methylclonazepam (HY-W399186). Methylclonazepam is a benzodiazepine with anxiolytic activity. Methylclonazepam inhibits the absorption of 5-hydroxytryptamine by Schistosoma mansoni. Methylclonazepam derivatives have anti-Schistosoma mansoni activity.
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Antimalarial agent 29
0 ImagesCat. No.: HY-155688CAS No.: 2821078-81-1Antimalarial agent 29 (compound 16) is an antimalarial agent that inhibits P. berghei liver stage parasite load with an EC50 of 5.2 μM.
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Antiparasitic agent-4
0 ImagesCat. No.: HY-146042CAS No.: 2253996-66-4Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM).
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DDD01035881
0 ImagesCat. No.: HY-187123CAS No.: 1396858-56-2DDD01035881 is a Plasmodium falciparum Pfs16 inhibitor, with an EC50 of 130 nM for exflagellation of male gametes of Plasmodium falciparum NF54 gametocytes. DDD01035881 stabilizes mature activated male gametocyte Pfs16, mimics the Pfs16-deficient phenotype, blocks the early formation process of male gametes before DNA replication, inhibits exflagellation, and exhibits male-specific activity with no activity against female gametes or asexual malaria parasite stages. DDD01035881 can be used in malaria-related research.
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DNMT-IN-3
0 ImagesCat. No.: HY-149289CAS No.: 1683516-27-9DNMT-IN-3 is an DNA Methyltransferase (DNMT) inhibitor, and plays an antimalarial role with IC50 of 60 nM against Plasmodium falciparum (Plasmodium). DNMT-IN-3 can be used for malaria related research.
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Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2
0 ImagesCat. No.: HY-P10215Ac-{Cpg}-Thr-Ala-{Ala(CO)}-Asp-{Cpg}-NH2 (compound 40) is a potent Plasmodium subtilisin-like protease 1 (SUB1) inhibitor. SUB1-IN-1 shows IC50 values of 12 nM and 10 nM against P. vivax and P. falciparum SUB1 (Pv- and PfSUB1), respectively.
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TSO-13
0 ImagesCat. No.: HY-172206TSO-13 is the inhibitor for the main cysteine protease of Trypanosoma cruzi Cruzipain with an IC50 of 2.2 μM. TSO-13 inhibits T. cruzi in Vero cell with an IC50 of 1.9 μM.
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Clindamycin phosphate (Standard)
0 ImagesSynonyms: Clindamycin 2-phosphate (Standard); U-28508 (Standard)Clindamycin phosphate (Standard) is the analytical standard of Clindamycin phosphate. This product is intended for research and analytical applications. Clindamycin phosphate (Clindamycin 2-phosphate) is a broad-spectrum bacteriostatic lincosamide antibiotic. Clindamycin phosphate is the proagent of Clindamycin (HY-B1455) with no antimicrobial activity in vitro but can be rapidly converted in vivo to the active parent agent, Clindamycin, by phosphatase ester hydrolysis. Clindamycin phosphate can be used for researching acne and bacterial vaginosis.
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DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS
0 ImagesCat. No.: HY-D1532CAS No.: 263718-22-5DABCYL-Glu-Arg-Nle-Phe-Leu-Ser-Phe-Pro-EDANS is a fluorescent dye, and can be applied in a fluorogenic substrate for an aspartyl proteinase from human malaria parasite.
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Naringenin 4',7-dimethyl ether
0 ImagesSynonyms: NRG-DMNaringenin 4',7-dimethyl ether, Naringenin (HY-N0100) derivative is an anti-seizure agent. Naringenin 4',7-dimethyl ether attenuates pentylenetetrazole-induced seizures in larval zebrafish and reduces seizures in the mouse 6-Hz psychomotor seizure model. Naringenin 4',7-dimethyl ether can be used for the research of epilepsy. Naringenin 4',7-dimethyl ether is an active agent against Leishmania mexicana (17.8 µM) and Trypanosoma brucei (17.5 µM).
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Antiparasitic agent-17
0 ImagesCat. No.: HY-149960CAS No.: 3043821-43-5Antiparasitic agent-17 (compound 5u) is an orally active antiparasitic agent. Antiparasitic agent-17 inhibits Chloroquine sensitive (Pf3D7) and Chloroquine resistant (PfK1) strain with IC50s of 0.96 μM and 1.67 μM, respectively.
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trans-Clopenthixol dihydrochloride (Standard)
0 ImagesSynonyms: (E)-Clopenthixol dihydrochloride (Standard)trans-Clopenthixol (dihydrochloride) (Standard) is the analytical standard of trans-Clopenthixol (dihydrochloride). This product is intended for research and analytical applications. trans-Clopenthixol ((E)-Clopenthixol) dihydrochloride is an antibiotic agent, without neuroleptic effect. trans-Clopenthixol can be used to inhibit Pseudomonas aeruginosa and Plasmodium falciparum in vitro[1][2].
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Antiparasitic agent-5
0 ImagesCat. No.: HY-146043CAS No.: 2494276-55-8Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM).
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Isatropolone A
0 ImagesCat. No.: HY-130993CAS No.: 2097813-40-4Isatropolone A, a natural product containing a 1,5-diketone moiety, is reisolated from Streptomyces Gö66. Isatropolone A shows potent activity against Leishmania donovani with an IC50 of 0.5 μM.
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Nyasol
0 ImagesCat. No.: HY-138050CAS No.: 96895-25-9Synonyms: (-)-Nyasol; (Z)-Hinokiresinol; cis-HinokiresinolNyasol ((-)-Nyasol) is an active compound that has antifungal, antibacterial, antileishmanial, hyaluronidase inhibition activities. Nyasol inhibits LTB4 binding to human neutrophils. Nyasol suppresses neuroinflammatory response through the inhibition of I-κB degradation in LPS (HY-D1056)-stimulated BV-2 microglial cells.
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Pefloxacin (Standard)
0 ImagesCat. No.: HY-B0147RCAS No.: 70458-92-3Synonyms: Pefloxacinium (Standard)Pefloxacin (Standard) (Pefloxacinium (Standard)) is the analytical standard of Pefloxacin (HY-B0147). This product is intended for research and analytical applications. Pefloxacin (Pefloxacinium) is a broad spectrum antibiotic. Pefloxacin blocks DNA replication by inhibiting DNA gyrase. Pefloxacin inhibits DNA relaxation catalyzed by topoisomerase I with an IC50 of 45 μg/mL. Pefloxacin exhibits antibacterial activity against Escherichia coli, Pseudomonas aeruginosa, and Bacteroides fragilis with MIC90s of 0.12, 4, and 16 mg/L, respectively. Pefloxacin has anti-Plasmodium yoelii infection activity. Pefloxacin increase UVA-induced edema and immunesuppression. Pefloxacin can be used for infection studies.
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Isogarcinol
0 ImagesCat. No.: HY-127087CAS No.: 71117-97-0Synonyms: Cambogin
