Antiparasitic agent-4
Antiparasitic agent-4 (compound 4q) has highly antiparasitic activity against Leishmania infantum (L. infantum) and Trypanosoma cruzi (T. cruzi) with IC50s of 8.51 μM and 2.20 μM, respectively. Antiparasitic agent-4 also has certain cytotoxicity against HepG2 (CC50 = 18.97 μM).
For research use only. We do not sell to patients.
- CAS No.: 2253996-66-4
- Formula: C16H13N3O2
- Molecular Weight:279.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Parasite Isoforms
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Biological Activity
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Trypanosoma |
Leishmania |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
18.97 μM
Compound: 4q
|
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
|
[PMID: 32590115] |
| HFF-1 | CC50 |
>64 μM
Compound: 4q
|
Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
|
[PMID: 32590115] |
Chemical Information
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CAS No. 2253996-66-4
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Molecular Weight 279.29
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Formula C16H13N3O2
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SMILES
OC(C(C1=NC(C2=CC=CC=C2)=NO1)=C)C3=CC=CN=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)