2494276-55-8
2494276-55-8
Chemical Structure
Antiparasitic agent-5
- CAS No.: 2494276-55-8
- Formula:C20H16ClN3O3
- Molecular Weight:381.81
IUPAC Name: 5-chloro-1-ethyl-3-hydroxy-3-(1-(3-phenyl-1,2,4-oxadiazol-5-yl)vinyl)indolin-2-one
InChIKey: WIYAKYWRWNNLES-UHFFFAOYSA-N
SMILES: O=C1N(CC)C2=C(C=C(Cl)C=C2)C1(O)C(C3=NC(C4=CC=CC=C4)=NO3)=C
Biological Activity: Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM)[1].
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Antiparasitic agent-5 | Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM). | |||||||||||||||||||||
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