Antiparasitic agent-5
Antiparasitic agent-5 (compound 8h) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.50 μM. Antiparasitic agent-5 also has certain cytotoxicity against HepG2 (CC50 = 6.78 μM).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2494276-55-8
- 分子式: C20H16ClN3O3
- 分子量:381.81
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
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生物活性
IC50: 2.50 μM (L. infantum)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HepG2 | CC50 |
6.78 μM
Compound: 8h
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Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HepG2 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
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[PMID: 32590115] |
| HFF-1 | CC50 |
>64 μM
Compound: 8h
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Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
Cytotoxicity against human HFF-1 cells assessed as reduction in cell viability incubated for 120 hrs by MTS assay
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[PMID: 32590115] |
化学情報
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CAS 番号 2494276-55-8
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分子量 381.81
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分子式 C20H16ClN3O3
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SMILES
O=C1N(CC)C2=C(C=C(Cl)C=C2)C1(O)C(C3=NC(C4=CC=CC=C4)=NO3)=C
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Antiparasitic agent-5 関連分類
HY-146043 関連分類
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