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Calmodulin Related Products (53)
Related Products (53)
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MLCK Peptide
0 ImagesCat. No.: HY-P10165CAS No.: 209251-64-9
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Fasciculic acid A
0 ImagesCat. No.: HY-N7733CAS No.: 126906-00-1Fasciculic acid A is a steroid that can be isolated from Hypholoma lateritium. Fasciculic acid B has antiinflammatory and calmodulin antagonistic activity.
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Aprindine hydrochloride (Standard)
0 ImagesCat. No.: HY-A0236ARCAS No.: 33237-74-0Aprindine hydrochloride (Standard) is the analytical reference standard of Aprindine hydrochloride (HY-A0236A). This product is used for research and analytical applications. Aprindine hydrochloride is an Ib-class anti-arrhythmic agent. Aprindine hydrochloride mainly exerts its effect by blocking sodium channels (INa), thereby reducing the excitability and conduction velocity of cardiac muscle cells. Aprindine hydrochloride significantly inhibits delayed potassium currents, which helps to prolong the atrial effective refractory period (AERP) and inhibit the occurrence of atrial fibrillation. Aprindine hydrochloride can also regulate intracellular calcium ion concentration by inhibiting Na+/Ca2+ exchange current (INCX), thereby further stabilizing cardiac electrical activity. Aprindine hydrochloride can be used for the study of atrial fibrillation (AF) and ventricular arrhythmias.
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W-7 hydrochloride (Standard)
0 ImagesCat. No.: HY-100912RCAS No.: 61714-27-0W-7 (hydrochloride) (Standard) is the analytical standard of W-7 (hydrochloride) (HY-100912). This product is intended for research and analytical applications. W-7 hydrochloride is a selective calmodulin antagonist. W-7 hydrochloride inhibits the Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase with IC50 values of 28 μM and 51 μM, respectively. W-7 hydrochloride induces apoptosis and has antitumor and vascular relaxing activity. W-7 hydrochloride is a blocker of Kv4.3 and can be used for research of arrhythmias.
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Elziverine
0 ImagesCat. No.: HY-106745CAS No.: 95520-81-3Synonyms: Ro 22-4839Elziverine (Ro 22-4839) is a brain circulation improvement agent with vasospasm antispasmodic effects. Elziverine is a calmodulin antagonist. Elziverine inhibits erythrocyte cell membrane rupture, platelet aggregation and lipid peroxidation.
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Psoralenoside (Standard)
0 ImagesCat. No.: HY-N7503RCAS No.: 905954-17-8Psoralenoside is a benzofuran glycoside from Psoralea corylifolia. Psoralenoside exhibits high binding affinities against histaminergic H1, calmodulin, and voltage-gated L-type calcium channels (E-value≥-6.5 Kcal/mol). Psoralenoside shows estrogen-like activity, osteoblastic proliferation accelerating activity, antitumor effects and antibacterial activity.
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Bromoriluzole
0 ImagesCat. No.: HY-W166106CAS No.: 144631-82-3Bromoriluzole is a derivative of Riluzole (HY-B0211). Bromoriluzole inhibits Ca2+ -dependent Calmodulin-SK4 channel interaction. Bromoriluzole is used for the research of neurodegenerative diseases.
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Calmidazolium chloride (Standard)
0 ImagesCat. No.: HY-103319RCAS No.: 57265-65-3Synonyms: R 24571 (Standard)Calmidazolium chloride (Standard) is the analytical standard of Calmidazolium chloride (HY-103319). This product is intended for research and analytical applications. Calmidazolium chloride (R 24571) is a calmodulin antagonist, antagonizing CaM-dependent phosphodiesterase and calmodulin-induced activation of erythrocyte Ca2+-transporting ATPase with IC50s of 0.15 and 0.35 μM, respectively. Also in anti-cancer research. Calmidazolium binds to calmodulin with a Kd of 3 nM.
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Bisindolylmaleimide VII
0 ImagesCat. No.: HY-137045CAS No.: 137592-47-3Bisindolylmaleimide VII is a potent inhibitor of calmodulin with high affinity for calmodulin (Kd=186.2 nM). Bisindolylmaleimide VII is used to study the role of calmodulin in cancer, neurodegenerative diseases, and muscle dysfunction.
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Metofenazate diethanesulfonate
0 ImagesCat. No.: HY-100263BCAS No.: 1674-48-2Synonyms: Methophenazine diethanesulfonateMetofenazate diethanesulfonate is a selective calmodulin inhibitor.
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Quisultidine
0 ImagesCat. No.: HY-124203CAS No.: 64099-44-1Synonyms: LM 24056Quisultidine (LM 24056) is an orally active phenothiazine derivative with both calmodulin (Calmodulin) inhibitory activity (with a IC50 of 55 μM against porcine calmodulin) and muscarinic acetylcholine receptor (mAChR) ligand activity (with a IC50 of 400 nM). It inhibits gastric acid and pepsin secretion, reduces circulating gastrin levels, and blocks histamine-stimulated gastric acid secretion. Quisultidine can be used in the research of duodenal ulcer.
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Arundic Acid (Standard)
0 ImagesCat. No.: HY-107661RCAS No.: 185517-21-9Synonyms: ONO-2506 (Standard); (R)-2-Propyloctanoic acid (Standard)Propiverine (hydrochloride) (Standard) is the analytical standard of Propiverine (hydrochloride). This product is intended for research and analytical applications. Propiverine hydrochloride is a bladder spasmolytic with calcium antagonistic and anticholinergic properties. Propiverine hydrochloride can be used for the research of overactive blaqdder and urinary incontinence.
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Khl 8430
0 ImagesCat. No.: HY-187595CAS No.: 114753-71-8Khl 8430 is a Calmodulin antagonist. It binds to both free calmodulin and calmodulin-enzyme complexes, thereby abolishing the regulatory effects of calmodulin on phosphofructokinase (PFA) and phosphodiesterase. Khl 8430 is applicable for studies of calmodulin-related signaling pathways.
