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Drug Derivative

Drug derivative

Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.

Productos relacionados con Drug Derivative (3822):

Cat. No. Nombre del producto Efecto Pureza Chemical Structure
  • HY-177967
    Antitumor agent-209
    Antitumor agent-209 (Compound 10g), a quinolone derivative, is an antitumor agent. Antitumor agent-209 can inhibit proliferation of HCT-116, RKO, DLD1, HepG2, BGC-823, NCI-H1650 and SK-OV-3 cells with IC50 values of 0.37, 0.58, 0.81, 0.79, 0.89, 0.78 and 0.89 μM.
    Antitumor agent-209
  • HY-167730
    Macluraxanthone
    Macluraxanthone is a natural xanthone.
    Macluraxanthone
  • HY-180820
    Dimethyl bisphenolate
    Dimethyl bisphenolate (Compound DMB) is a natural neolignan derivative with orally active anti-tumor activity. Dimethyl bisphenolate can inhibit cancer cells proliferation, invasion and migration. Dimethyl bisphenolate can activate the p53 signaling pathway, upregulate the expression of p21 protein, inhibit the activity of the CDK1-cyclin B1 complex, and cause cells to stall at the G2/M phase. Dimethyl bisphenolate can induce ROS production, upregulate pro-apoptotic proteins Noxa and Bim, downregulate anti-apoptotic protein Bcl-2, activate caspase-9 and caspase-3, and ultimately induce cell apoptosis. Dimethyl bisphenolate can be used for research of glioblastoma.
    Dimethyl bisphenolate
  • HY-N6821R
    2-O-α-D-Glucopyranosyl-L-ascorbic Acid (Standard)
    2-O-α-D-Glucopyranosyl-L-ascorbic Acid (Standard) is the analytical standard of 2-O-α-D-Glucopyranosyl-L-ascorbic Acid. This product is intended for research and analytical applications. 2-O-α-D-Glucopyranosyl-L-ascorbic Acid is a glucoside derivative of ascorbic acid, shows anti-cancer activity after enzymatic hydrolysis to ascorbic acid.
    2-O-α-D-Glucopyranosyl-L-ascorbic Acid (Standard)
  • HY-N17090
    Macrophylloside A
    Macrophylloside A is a natural iridoid.
    Macrophylloside A
  • HY-N13806
    11β,13-Dihydrotaraxinic acid
    11β,13-Dihydrotaraxinic acid is a natural sesquiterpene.
    11β,13-Dihydrotaraxinic acid
  • HY-N9120
    6,11-Di-O-acetylalbrassitriol
    6,11-Di-O-acetylalbrassitriol is a natural sesquiterpene.
    6,11-Di-O-acetylalbrassitriol
  • HY-N7623
    Ursonic acid methyl ester
    Ursonic acid methyl ester is an esterified derivative of Ursolic acid (HY-N0140). Ursonic acid methyl ester shows growth inhibitory activity against four tumor cell lines, HL-60, BGC, Bel-7402 and Hela with ED50 values of >100 µg/ml.
    Ursonic acid methyl ester
  • HY-165019
    1-(3,4-Dichlorophenyl)-2-(dimethylamino)-1-propanone hydrochloride
    1-(3,4-Dichlorophenyl)-2-(dimethylamino)-1-propanone hydrochloride is a drug derivative.
    1-(3,4-Dichlorophenyl)-2-(dimethylamino)-1-propanone hydrochloride
  • HY-160829
    Karenitecin-NH2
    Karenitecin-NH2 (Cositecan-NH2) (DB-173) is a Camptothecin (HY-16560) analogue with antitumor activity.
    Karenitecin-NH2
  • HY-148653
    (+)-C-BVDU
    (+)-C-BVDU is an active compound.
    (+)-C-BVDU
  • HY-N16681
    Oxyphyllenodiol A
    Oxyphyllenodiol A is a natural sesquiterpene.
    Oxyphyllenodiol A
  • HY-183786
    Anticancer agent 327
    Anticancer agent 327, a fluorescent Andrographolide (HY-N0191) derivative, is an NF-κB p50 inhibitor. Anticancer agent 327 covalently binds to the p50 subunit of NF-κB. Anticancer agent 327 reduces levels of multiple oncogenic p53 proteins via the autophagy/lysosome pathway. Anticancer agent 327 can be used for the research of pancreatic ductal adenocarcinoma (Ex/Em = 488/515 nm)[1].
    Anticancer agent 327
  • HY-N17360
    4,10-Epizedoarondiol
    4,10-Epizedoarondiol is a natural product that can be found in Curcuma zedoaria.
    4,10-Epizedoarondiol
  • HY-N16902
    Vibralactone L
    Vibralactone L is a natural sesquiterpene.
    Vibralactone L
  • HY-N13784
    Flaccidinin
    Flaccidinin is a natural phenolic compound.
    Flaccidinin
  • HY-N17877
    Loniceroside A
    Loniceroside A is a triterpenoid saponin found in the aerial parts of Lonicera japonica.
    Loniceroside A
  • HY-163375
    Methyl cis-12-octadecenoate
    		99.89%
    Methyl cis-12-octadecenoate is a derivative of Oleic aicd (HY-N1446), which is obtained via the witting reaction and used in metabolism studies in humans.
    Methyl cis-12-octadecenoate
  • HY-N17070
    Penthoroside B
    Penthoroside B is a natural phenolic compound.
    Penthoroside B
  • HY-179628
    STING agonist-49-CO-C2-mal-Cys
    STING agonist-49-CO-C2-mal-Cys (compound 2), the derivative of STING agonist-49-CO-C2-mal (HY-179627), is the product of ADC catabolism and payload release, exhibits antitumor activity in vivo.
    STING agonist-49-CO-C2-mal-Cys