55275-64-4
Chemical Structure
AMP-404
- CAS No.: 55275-64-4
- Formula:C10H9N3O
- Molecular Weight:187.20
IUPAC Name: 2-cyano-N-phenylaziridine-1-carboxamide
InChIKey: BXBIBOQGYLPODI-UHFFFAOYSA-N
SMILES: N#CC1N(C(=O)NC=2C=CC=CC2)C1
Biological Activity: AMP-404 is an Imexon (HY-15385)-derived antitumor agent with dual functions as a cytotoxin and growth inhibitor. AMP-404 exerts significant cytotoxic effects against various sensitive, drug-resistant and primary human tumor cells, including myeloma, breast cancer, melanoma, ovarian cancer and sarcoma cells. AMP-404 effectively inhibits the growth of rat PIE 2-3 sarcoma in vivo and exhibits remarkable in vivo efficacy[1][2].
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AMP-404 | AMP-404 is an Imexon (HY-15385)-derived antitumor agent with dual functions as a cytotoxin and growth inhibitor. AMP-404 exerts significant cytotoxic effects against various sensitive, drug-resistant and primary human tumor cells, including myeloma, breast cancer, melanoma, ovarian cancer and sarcoma cells. AMP-404 effectively inhibits the growth of rat PIE 2-3 sarcoma in vivo and exhibits remarkable in vivo efficacy. | |||||||||||||||||||||
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Keywords
