Drug Derivative
Drug derivative
Drug derivatives are derived from parent compounds. They replace or add atoms and groups through chemical reactions to optimize the various properties of the parent compound and reduce side effects. The application of drug derivatives provides a diverse compound library for drug research and development and accelerates the discovery of new drugs. For example, urea derivatives Glibenclamide can prolong the blood sugar-lowering effect of anti-diabetic drugs.
References:
- [1]. Vardanyan RS, et al. Fentanyl-related compounds and derivatives: current status and future prospects for pharmaceutical applications. Future Med Chem. 2014 Mar;6(4):385-412.x
- [2]. Ghosh AK, et al. Urea Derivatives in Modern Drug Discovery and Medicinal Chemistry. J Med Chem. 2020 Mar 26;63(6):2751-2788.x
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Drug Derivative Inhibitors
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Drug Derivative Related Products (4032)
Related Products (4032)
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Aloracetam
0 ImagesCat. No.: HY-148605CAS No.: 119610-26-3Aloracetam is a γ-aminobutyric acid cyclic derivative that can pass through the blood-brain barrier and has a significant enhancing cognitive function effect. Aloracetam improves the blood perfusion of brain tissue, increases the synthesis of proteins, ATP and acetylcholine in the brain, enhances the excitatory conduction effect of cholinergic nerves, and reduces the damage to brain tissue caused by cerebral vascular diseases. Aloracetam also has certain anti-epileptic, anti-inflammatory, analgesic and anti-depressant effects.
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Moluccanin diacetate
0 ImagesCat. No.: HY-N3250CAS No.: 121700-27-4Moluccanin diacetate is a natural lignan.
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Dicliripariside A
0 ImagesCat. No.: HY-N13753CAS No.: 491613-65-1Dicliripariside A is a natural terpenoid.
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8β-Tigloyloxycostunolide
0 ImagesCat. No.: HY-N9276CAS No.: 96850-21-48β-Tigloyloxycostunolide is a natural sesquiterpene.
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(1S,16R)-1-Hydroxycryptotanshinone anhydride
0 ImagesCat. No.: HY-N17059CAS No.: 2301967-86-0(1S,16R)-1-Hydroxycryptotanshinone anhydride is a natural diterpene.
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(+)-Mornaphthoate B
0 ImagesCat. No.: HY-N17556CAS No.: 2409077-00-3(+)-Mornaphthoate B is a Methyl 2-naphthoate derivative. (+)-Mornaphthoate B can be isolated from the roots of Morinda officinalis var. officinalis. (+)-Mornaphthoate B exhibits no activity against Acetylcholinesterase and Butyrylcholinesterase. (+)-Mornaphthoate B can be used in the research of non-small cell lung cancer and triple-negative breast cancer.
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28-O-Tigloylgymnemagenin
0 ImagesCat. No.: HY-129223ACAS No.: 3032078-44-428-O-Tigloylgymnemagenin (I) is a natural anticancer agent. 28-O-Tigloylgymnemagenin has good anti-proliferation activity on human acute myeloid leukemia cells and non-small cell lung cancer (NSCLC). 28-O-Tigloylgymnemagenin can be used for the study of leukemia and lung cancer.
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Iododoxorubicin
0 ImagesCat. No.: HY-101003CAS No.: 83997-75-5Iododoxorubicin is a derivative of Doxorubicin (HY-15142A) and anticancer agent. Iododoxorubicin has stronger activity against Lewis lung carcinoma than Doxorubicin.
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5-EAPB hydrochloride
0 ImagesCat. No.: HY-129822CAS No.: 1823776-22-25-EAPB hydrochloride is a benzofuran.
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N-Cyclopropyl-4-iodobenzamide
0 ImagesN-Cyclopropyl-4-iodobenzamide is an active molecule.
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Antitumor agent-21
0 ImagesCat. No.: HY-107470CAS No.: 1256037-58-7Antitumor agent-21 is an aryl-quinolin derivative, with potential anticancer, anti-inflammatory, anti-proliferative, anti-hormonal effects and inhibition of vasculogenic mimicry .
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HDAC8/PIM1-IN-1
0 ImagesCat. No.: HY-189297HDAC8/PIM1-IN-1 is a synthetic multi-target-directed ligand (MTDL) derived from 2-ureido-6-nitrobenzamide, and computational simulations predict it to be a dual-target inhibitor of HDAC8 and PIM1. HDAC8/PIM1-IN-1 holds potential for applications in research related to cancer and neurodegenerative diseases.
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RAD-243
0 ImagesCat. No.: HY-113857CAS No.: 103825-20-3RAD-243 is an active compound.
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(R)-Sophoramine
0 ImagesCat. No.: HY-N3198CAS No.: 52932-74-8Synonyms: (R)-(-)-Sophoramine; Neosophoramine(R)-Sophoramine ((R)-(-)-Sophoramine) is a natural alkaloid.
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Difenoxuron
0 ImagesCat. No.: HY-121880CAS No.: 14214-32-5Difenoxuron is an active compound.
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para-Methylaminorex
0 ImagesCat. No.: HY-W681674CAS No.: 959249-62-8para-Methylaminorex is structurally similar to known stimulants.
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Wedelobatin A
0 ImagesCat. No.: HY-N16908CAS No.: 1589488-34-5Wedelobatin A is a natural diterpene.
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Acronyculatin Q
0 ImagesCat. No.: HY-N16965CAS No.: 2287183-54-2Acronyculatin Q is a natural phenolic compound.
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Stelleranol
0 ImagesCat. No.: HY-N17168CAS No.: 795308-62-2Stelleranol is a natural flavonoid.
