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Drug Intermediate

Drug Iintermediate

Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].

Drug Intermediate Related Products (4365):

Cat. No. Product Name Effect Purity Chemical Structure
  • HY-44680
    L-Cystine N-carboxyanhydride
    L-Cystine N-carboxyanhydride can be used for synthesis of polyamino acid carrier for anti-tumor agent delivery.
    L-Cystine N-carboxyanhydride
  • HY-145866
    Antiproliferative agent-3
    Antiproliferative agent-3 (comp 4) shows the highest potency for MCF-7 cells (IC50 = 0.19 nM).
    Antiproliferative agent-3
  • HY-173703
    β-Glu-PAB(CH2NH2)-Exatecan
    β-Glu-PAB(CH2NH2)-Exatecan (Compound 9a) is a topoisomerase I inhibitor. β-Glu-PAB(CH2NH2)-Exatecan binds to the topoisomerase I-DNA complex to prevent DNA strand reconnection, thereby inducing DNA breakage and cell apoptosis. β-Glu-PAB(CH2NH2)-Exatecan can be specifically cleaved by β-glucuronidase highly expressed in the tumor microenvironment to release Exatecan for cytotoxic effect. β-Glu-PAB(CH2NH2)-Exatecan is also an intermediate of Mal((3S,3aR,6S,6aR) -hexahydrofuro [3, 2-B]furan-3,6-diamine-PEG12)-β -Glu-Pab-Exatecan. β-Glu-PAB(CH2NH2)-Exatecan is promising for research of cancers.
    β-Glu-PAB(CH2NH2)-Exatecan
  • HY-185602
    m7G(5')vppp(5')(2'OMeA)pG triammonium
    m7G(5')vppp(5')(2'OMeA)pG 100mM Ammonium Solution is a cap analog that can be used for the synthesis of mRNA.
    m7G(5')vppp(5')(2'OMeA)pG triammonium
  • HY-N16458
    FI-3
    FI-3 is a polycyclic tetramate macrolactam biosynthetic intermediate found in Streptomyces sp. SPB78. FI-3 is promising for research of antibiotics.
    FI-3
  • HY-59243S
    4,7-Dichloroquinoline-15N
    4,7-Dichloroquinoline-15N is the 15N labeled 4,7-Dichloroquinoline (HY-59243). 4,7-Dichloroquinoline is a dichloro-substituted quinoline that can be used for the synthesis of other active compounds.
    4,7-Dichloroquinoline-<sup>15</sup>N
  • HY-109056A
    Elsulfavirine sodium
    Elsulfavirine sodium (R-1206) is an orally active human carbonic anhydrase (carbonic anhydrase, CA) inhibitor and an allosteric inhibitor of HIV-1 non-nucleoside reverse transcriptase (NNRT). Elsulfavirine sodium also targets and blocks the interaction between adenylosuccinate lyase (ADSL) and insulin-induced gene proteins INSIG1/2, blocks SREBP-1-mediated de novo lipid synthesis, and inhibits the proliferation of liver cancer cells. The combination of Elsulfavirine sodium and Lenvatinib (HY-10981) produces a synergistic anti-tumor effect. Elsulfavirine sodium is converted into the active metabolite VM1500A in vivo, blocks the DNA polymerase activity of reverse transcriptase, and inhibits HIV-1 replication. Elsulfavirine sodium exhibits a Ki of 1960 nM-52400 nM against human carbonic anhydrase isoforms including I, VII, VI, VA, VB, IX, XIII, XIV. Elsulfavirine sodium is used in studies related to HIV-1 infection and liver cancer.
    Elsulfavirine sodium
  • HY-N3994
    16α,17α-Epoxyprogesterone
    16α,17α-Epoxyprogesterone is an important steroid, serving as an intermediate for many hormonal drugs such as Hydrocortisone (HY-N0583) and Megestrol (HY-B1834). 16α,17α-Epoxyprogesterone can further biotransform into another significant intermediate, 11α-hydroxy-16α,17α-epoxyprogesterone, to manufacture additional compounds.
    16α,17α-Epoxyprogesterone
  • HY-W099339
    N-Ethylnicotinamide
    N-Ethylnicotinamide is a compound with weak vasodilatory activity. N-Ethylnicotinamide also serves as the core scaffold of the antianginal agent Nicorandil (HY-B0341) and its derivatives.
    N-Ethylnicotinamide
  • HY-176028
    N-Stearoyl-DPPE ammonium
    N-Stearoyl-DPPE ammonium is a type of N-acylphosphatidylethanolamine (NAPE). N-Stearoyl-DPPE ammonium is an important intermediate in the endocannabinoid biosynthesis pathway.
    N-Stearoyl-DPPE ammonium
  • HY-W343771
    H-Tyr-Gly-OH
    H-Tyr-Gly-OH is an amino acid building block commonly used in biochemical and peptide synthesis.
    H-Tyr-Gly-OH
  • HY-135380R
    Atorvastatin acetonide tert-butyl ester (Standard)
    Atorvastatin acetonide tert-butyl ester (Standard) is the analytical standard of Atorvastatin acetonide tert-butyl ester. This product is intended for research and analytical applications. Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an orally active HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
    Atorvastatin acetonide tert-butyl ester (Standard)
  • HY-78004
    Bibenzyl
    		99.97%
    Bibenzyl (s-Diphenylethane; Dibenzyl) is a compound containing two benzyl groups. Its derivatives possess various activities such as antioxidant, anti-inflammatory, and anti-cancer properties.
    Bibenzyl
  • HY-108399
    Fingolimod impurity 3
    Fingolimod impurity 3 is an impurity of Fingolimod (HY-11063).
    Fingolimod impurity 3
  • HY-153151
    Fmoc-DON-Boc
    Fmoc-DON-Boc (Compound 8b) is an Fmoc-protected compound that can be used for the synthesis of proagent of 6-diazo-5-oxo-L-norleucine (DON; HY-108357). DON is a glutamine antagonist.
    Fmoc-DON-Boc
  • HY-W087952R
    (R)-(-)-2-Butanol (Standard)
    Ginsenoside Rg1 (Standard) is the analytical standard of Ginsenoside Rg1. This product is intended for research and analytical applications. Ginsenoside Rg1 is one of the major active components of Panax ginseng. Ginsenoside Rg1 ameliorates the impaired cognitive function, displays promising effects by reducing cerebral Aβ levels. Ginsenoside Rg1 also reduces NF-κB nuclear translocation.
    (R)-(-)-2-Butanol (Standard)
  • HY-132988
    Fmoc-Tyr(3-F,tBu)-OH
    		99.98%
    Fmoc-Tyr(3-F,tBu)-OH is an Fmoc-labeled amino acid derivative. Fmoc-Tyr(3-F,tBu)-OH can be used for peptide synthesis.
    Fmoc-Tyr(3-F,tBu)-OH
  • HY-165323
    Pirisudanol
    		Inhibitor
    Pirisudanol (pyrisuccideanol) is a psychostimulant. Pirisudanol can be used for the research of neurological disease, such as depression.
    Pirisudanol
  • HY-170956
    BTN3A1 ligand-1
    BTN3A1 ligand-1 (Compound 26b) is a triazole-containing aryl/acyloxyalkyl phosphonate prodrug. BTN3A1 ligand-1 can stimulate T cell proliferation (EC50 : 0.49 nM) and interferon γ secretion. BTN3A1 ligand-1 has certain plasma stability and can be used in related immunotherapy research.
    BTN3A1 ligand-1
  • HY-W353231
    3-Phenanthrylamine
    3-Phenanthrylamine is an intermediate. 3-Phenanthrylamine has potential breast carcinogenic activity.
    3-Phenanthrylamine