Drug Intermediate
Drug Iintermediate
Drug intermediates are used as raw materials for the production of bulk drugs, or they can refer to a material produced during synthesis of an API that must undergo further molecular change or processing before it becomes an API. Drug intermediates are hygienically formulated using high grade raw materials and they are used in the pharmaceutical and cosmetic industry[1][2].
References:
- [1]. Ma HC, et al. Homochiral Covalent Organic Framework for Catalytic Asymmetric Synthesis of a Drug Intermediate. J Am Chem Soc. 2020 Jul 22;142(29):12574-12578. [Content Brief]
- [2]. Ramachary D B, et al. Development of pharmaceutical drugs, drug intermediates and ingredients by using direct organo‐click reactions[J]. 2008.
All Product Categories
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Drug Intermediate Related Products (4712)
Related Products (4712)
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Stemmadenine
0 ImagesCat. No.: HY-N19310CAS No.: 10012-73-4Stemmadenine is a strychnos-type monoterpenoid indole alkaloid that serves as a biosynthetic precursor of the monoterpenoid indole alkaloid skeleton.
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4-Methylethylbenzene
0 Images4-Methylethylbenzene is a volatile aromatic hydrocarbon compound. 4-Methylethylbenzene can be isolated from the essential oil of the peels of Juglans nigra L. .
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NRMA-I
0 ImagesCat. No.: HY-164512CAS No.: 1417653-47-4NRMA-I is the amide produrg of the small molecule nuclear receptor modulator. NRMA-I exhibits a higher exposure in the brain, indicating that a good blood-brain barrier (BBB) penetration. NRMA-I can be used for research of central nervous system diseases related to nuclear receptors, such as Alzheimer's disease and Parkinson's disease.
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Octadecanedioic acid (Standard)
0 ImagesOctadecanedioic acid (Standard) is an analytical standard of Octadecanedioic acid (HY-W005178). This product is intended for research and analytical applications. Octadecanedioic acid is an aliphatic dibasic acid and also serves as a comonomer unit for biodegradable oligo (ester amide).
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XL388-C2-amide-PEG9-NH2 hydrochloride
0 ImagesCat. No.: HY-139085AXL388-C2-amide-PEG9-NH2 hydrochloride is an intermediate used in the synthesis of C26-linked Rapamycin analog.
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DL-Decanoylcarnitine chloride
0 ImagesCat. No.: HY-100955CAS No.: 18822-87-2DL-Decanoylcarnitine chloride is an intermediate in lipid metabolism.
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3-[(4-Aminobutyl)amino]propanenitrile
![3-[(4-Aminobutyl)amino]propanenitrile](https://file.medchemexpress.com/product_pic/hy-187138.gif "Click to View 3-[(4-Aminobutyl)amino]propanenitrile Product Detail")
0 Images3-[(4-Aminobutyl) amino]propanenitrile is a polyamine analog and also a synthetic intermediate. 3-[(4-Aminobutyl) amino]propanenitrile exhibits no growth inhibitory activity against cancer cells in culture medium supplemented with calf serum containing bovine plasma amine oxidase. 3-[(4-Aminobutyl) amino]propanenitrile can be used to prepare N1-substituted spermidine derivatives required for boron neutron capture therapy and positron emission tomography tumor imaging.
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Palustric acid (Standard)
0 ImagesCat. No.: HY-133593RCAS No.: 1945-53-5Palustric acid (Standard) is the analytical standard of Palustric acid (HY-133593). This product is intended for research and analytical applications. Palustric acid is an abietane-type diterpenoid that is found in Pinus palustris, Pinus caribaea, and rosin.
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(2R,3S,4R,5R)-GlcAc-GlcA
0 ImagesCat. No.: HY-402202CAS No.: 3018017-12-1(2R,3S,4R,5R)-GlcAc-GlcA is a hexose derivative that can be used in the synthesis of ADC linkers.
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Gal-GIcNAc-oxazoline
0 ImagesCat. No.: HY-156232CAS No.: 2855124-88-6Gal-GlcNAc-oxazoline is an intermediate bearing an azido group, which can be used in studies related to the synthesis of antibody-drug conjugates (ADC) via click chemistry.
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1-Adamantanol-d15
0 ImagesCat. No.: HY-Y0531SCAS No.: 33830-11-4Synonyms: Tricyclo[3.3.1.1~3,7~]decan-1-ol-d151-Adamantanol-d15 (Tricyclo[3.3.1.1~3,7~]decan-1-ol-d15) is the deuterium labeled 1-Adamantanol (HY-Y0531). 1-Adamantanol (Tricyclo[3.3.1.1~3,7~]decan-1-ol) is a hydroxylated derivative of Adamantane (HY-N2427). 1-Adamantanol serves as a substrate for regioselective hydroxylation reactions in Streptomyces strain SA8. 1-Adamantanol can form acrylate derivatives, which are used as photoresist layer materials.
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phoBET1
0 ImagesCat. No.: HY-149328CAS No.: 3033545-34-2phoBET1 is a photolabile PROTAC molecule that, upon photoactivation, functions as a BRD4 PROTAC degrader to trigger BRD4 degradation via the ubiquitin-proteasome system. Activated phoBET1 induces cancer cell apoptosis and inhibits tumor growth in xenograft mouse models. In its inactive caged state, phoBET1 exhibits only extremely low antiproliferative activity against cancer cells. phoBET1 can be applied in studies related to acute myeloid leukemia.
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Alstonidine
0 ImagesCat. No.: HY-119537CAS No.: 25394-75-6Alstonidine is a methyl ester compound that can be converted to Alstonidinic acid by saponification and can be regenerated by diazomethane.
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Boc-PNA-T-OH
0 ImagesCat. No.: HY-W784626CAS No.: 139166-80-6Boc-PNA-T-OH is a thymine-containing peptide nucleic acid monomer and solid-phase synthesis building block.
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LAF389
0 ImagesCat. No.: HY-118953CAS No.: 270902-51-7LAF389, a prodrug of LAF153 (HY-183876), is a methionine aminopeptidase (MetAps) inhibitor with an IC50 of 800 nM against MetAp2, and exhibits a maximum inhibition rate of 20% against MetAp1 at 300 nM. LAF389 possesses antiproliferative, antiangiogenic and cytotoxic activities. LAF389 can be used in research related to cancers such as advanced solid tumors.
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BuChE-IN-22
0 ImagesCat. No.: HY-181865BuChE-IN-22 is a pseudo-irreversible butyrylcholinesterase (BuChE) inhibitor, with IC50 values of 4 nM and 157 nM against hBuChE and hAChE, respectively. It also acts as a prodrug of 7-hydroxysertraline. BuChE-IN-22 releases 7-hydroxysertraline during BuChE inhibition. BuChE-IN-22 completely reverses Aβ25-35-induced short-term and long-term memory impairments in a mouse model of Alzheimer's disease. BuChE-IN-22 can be used in research related to Alzheimer's disease.
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VYPFPGPIHN
0 ImagesCat. No.: HY-P11740CAS No.: 157173-35-8VYPFPGPIHN is a precursor peptide of β-casomorphin (HY-P0179) and also an ACE inhibitor (IC50 = 123 μM). VYPFPGPIHN resists hydrolysis by peptidases associated with intestinal cell monolayers, maintaining structural integrity and ACE inhibitory activity. VYPFPGPIHN is not extensively taken up or transported by differentiated intestinal cell monolayers.
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Desalkylquazepam
0 ImagesCat. No.: HY-W664824CAS No.: 1645-32-5Synonyms: N-DesmethylquazepamDesalkylquazepam (Compound 23; N-Desmethylquazepam) is a precursor in the synthesis of triazolobenzodiazepines. Desalkylquazepam is a mAChR modulator (EC 50 = 0.317 µM).
