2. Metabolic Enzyme/Protease Others
  3. Angiotensin-converting Enzyme (ACE) Drug Intermediate
  4. VYPFPGPIHN

VYPFPGPIHN is a precursor peptide of β-casomorphin (HY-P0179) and also an ACE inhibitor (IC50 = 123 μM). VYPFPGPIHN resists hydrolysis by peptidases associated with intestinal cell monolayers, maintaining structural integrity and ACE inhibitory activity. VYPFPGPIHN is not extensively taken up or transported by differentiated intestinal cell monolayers.

For research use only. We do not sell to patients.

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VYPFPGPIHN

VYPFPGPIHN Chemical Structure

CAS No. : 157173-35-8

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VYPFPGPIHN Related Antibodies

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Description

VYPFPGPIHN is a precursor peptide of β-casomorphin (HY-P0179) and also an ACE inhibitor (IC50 = 123 μM). VYPFPGPIHN resists hydrolysis by peptidases associated with intestinal cell monolayers, maintaining structural integrity and ACE inhibitory activity. VYPFPGPIHN is not extensively taken up or transported by differentiated intestinal cell monolayers[1].

In Vitro

The peptide VYPFPGPIHN (500 μM; 120 min) incubated with differentiated Caco-2 cell monolayers does not change its ACE inhibitory activity, and no transport of the peptide across the monolayer is detected[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

VYPFPGPIHN Related Antibodies
Molecular Weight

1140.29

Formula

C56H77N13O13
CAS No.
Sequence

Val-Tyr-Pro-Phe-Pro-Gly-Pro-Ile-His-Asn
Sequence Shortening

VYPFPGPIHN
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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VYPFPGPIHN Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

VYPFPGPIHN157173-35-8Angiotensin-converting Enzyme (ACE)Drug IntermediateDrug Iintermediateintestinal cell monolayer-associated peptidasesACECaco-2 cell monolayersintestinal cell monolayersInhibitorinhibitorinhibit

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