Isotope-Labeled Compounds

Isotope-labeled compounds are chemical substances in which some atoms in their molecules are replaced by isotope atoms. The range of stable isotope products can cover from gases to complex molecules. Isotope-labeled compounds could provide a site-specific investigation of structures, making molecules easily detectable by mass spectrometry and NMR, and maintaining the physico-chemical properties of the target molecule at the same time. MCE isotope-labeled compounds are all stable isotope-labeled compounds and are non-radioactive labeled substances. MCE isotope-labeled compounds are unique tools for identifying and understanding biological and chemical processes. Stable isotope-labeled products are now getting more and more popular among scientists. The scope of application is gradually penetrating into various scientific fields, such as life sciences, food and medicine, agriculture, environment, geology, etc. Stable isotope-labeled compounds have a wide range of applications in the Life Science areas, such as Metabolomics, Proteomics, Clinical studies, Deuterium drugs, etc.

Isotope-Labeled Compounds Inhibitors (4)

Isotope-Labeled Compounds Related Products (10876):

Cat. No.	Product Name	Effect	Purity	Chemical Structure

HY-N0830S18

Palmitic acid-d		99.90%
Palmitic acid-d is the deuterium labeled Palmitic acid. Palmitic acid is a long-chain saturated fatty acid commonly found in both animals and plants. PA can induce the expression of glucose-regulated protein 78 (GRP78) and CCAAT/enhancer binding protein homologous protein (CHOP) in in mouse granulosa cells.

HY-146914S

16:0-18:0-16:0 TG-d₅		99.90%
16:0-18:0-16:0 TG-d₅ is deuterium labeled 16:0-18:0-16:0 TG.

HY-W779296

Potassium thiocyanate-¹³C,¹⁵N		98.10%
Potassium thiocyanate-¹³C,¹⁵N (Potassium rhodanide-¹³C,¹⁵N) is ¹³C and ¹⁵N labeled Potassium thiocyanate.

HY-W010708S1

Cholesteryl palmitate-d₇		99.00%
Cholesteryl palmitate-d₇ is deuterium labeled Cholesteryl palmitate. Cholesteryl palmitate is a useful prognostic biomarker for chronic interstitial pneumonia (CIP).

HY-B0236S

6-Aminocaproic acid-d₆		99.93%
6-Aminocaproic acid-d₆ is deuterium labeled 6-Aminocaproic acid. 6-Aminocaproic acid (EACA), a monoamino carboxylic acid, is a potent and orally active inhibitor of plasmin and plasminogen. 6-Aminocaproic acid is a potent antifibrinolytic agent. 6-Aminocaproic acid prevents clot lysis through the competitive binding of lysine residues on plasminogen, inhibiting plasmin formation and reducing fibrinolysis. 6-Aminocaproic acid can be used for the research of bleeding disorders.

HY-N0583S1

Hydrocortisone-d₇		99.91%
Hydrocortisone-d₇ is the deuterium labeled Hydrocortisone. Hydrocortisone (Cortisol) is a steroid hormone or glucocorticoid secreted by the adrenal cortex.

HY-14879S2

Avibactam sodium salt-¹³C₅		99.9%
Avibactam sodium salt-¹³C₅ (NXL-104-¹³C₅) is ¹³C labeled Avibactam (sodium). Avibactam sodium (NXL-104) is a covalent and reversible non-β-lactam β-lactamase inhibitor which inhibits β-lactamase TEM-1 and CTX-M-15 with IC₅₀s of 8 nM and 5 nM, respectively.

HY-N0684S3

Vitamin K1-¹³C₆		99.12%
Vitamin K1-¹³C₆ is the ¹³C-labeled Vitamin K1. Vitamin K1 a naturally occurring vitamin required for blood coagulation and bone and vascular metabolism.

HY-B0016S

Capecitabine-d₁₁		99.90%
Capecitabine-d₁₁ is the deuterium labeled Capecitabine. Capecitabine is an oral proagent that is converted to its active metabolite, 5-FU, by thymidine phosphorylase.

HY-N0455AS5

L-Arginine-1,2-¹³C₂ hydrochloride		98.9%
L-Arginine-1,2-¹³C₂ (hydrochloride) is the ¹³C-labeled L-Arginine hydrochloride. L-Arginine hydrochloride ((S)-(+)-Arginine hydrochloride) is the nitrogen donor for synthesis of nitric oxide, a potent vasodilator that is deficient during times of sickle cell crisis.

HY-W587724S

6β-Hydroxy Cortisol-d₄		99.14%
6β-Hydroxy Cortisol-d₄ is a deuterium labeled compound.

HY-G0017S

N-Desmethyl imatinib-d₈		99.95%
N-Desmethyl imatinib-d₈ is a deuterium labeled Imatinib metabolite N-Desmethyl Imatinib (HY-G0017). N‑Desmethyl imatinib (Norimatinib) is an active metabolite of Imatinib (HY-15463), a selective c‑Abl inhibitor, and a substrate of P‑glycoprotein. N-Desmethyl imatinib binds to the c-Abl catalytic domain to prevent substrate phosphorylation, inhibits c-Abl-mediated α-synuclein activation and downstream inflammatory signaling pathways. N-Desmethyl imatinib induces apoptosis in K562 human leukemia cells. N-Desmethyl imatinib exhibits significantly elevated plasma levels in gastrointestinal stromal tumor (GIST) settings following mild SARS CoV 2 infection. N-Desmethyl imatinib can be used for the research of Parkinson’s disease, gastrointestinal stromal tumor, and chronic myeloid leukemia.

HY-W009162S5

Cytidine 5′-monophosphate-¹³C₉,¹⁵N₃ dilithium		99.80%
Cytidine 5′-monophosphate-¹³C₉,¹⁵N₃ (5'-Cytidylic acid-¹³C₉,¹⁵N₃ dilithium; 5'-CMP-¹³C₉,¹⁵N₃) dilithium is ¹³C and ¹⁵N-labeled Cytidine 5'-monophosphate (HY-W009162). Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide which is used as a monomer in RNA. Cytidine 5'-monophosphate consists of the nucleobase cytosine, the pentose sugar ribose, and the phosphate group.

HY-B0803S1

Lumefantrine-d₉
Lumefantrine-d₉ is the deuterium labeled Lumefantrine. Lumefantrine is an antimalarial drug, used in combination with Artemether. The artemether-lumefantrine (AL) as the first- and second-line anti-malarial drugs.

HY-113076S

Thiamine pyrophosphate-d₃
Thiamine pyrophosphate-d₃ is the deuterium labeled Thiamine pyrophosphate. Thiamine pyrophosphate is the coenzyme form of Vitamin B1 and is a required intermediate in the pyruvate dehydrogenase complex and the ketoglutarate dehydrogenase complex.

HY-N0658S

L-Threonine-¹⁵N		98.0%
L-Threonine-¹⁵N is the ¹⁵N-labeled L-Threonine. L-Threonine is a natural amino acid, can be produced by microbial fermentation, and is used in food, medicine, or feed.

HY-14268S1

Febuxostat-d₇		99.55%
Febuxostat-d₇ is deuterium labeled Febuxostat. Febuxostat (TEI 6720) is selective xanthine oxidase inhibitor with a K_i of 0.6 nM.

HY-Y0966S7

Glycine-2-¹³C,¹⁵N		98.0%
Glycine-2-¹³C,¹⁵N is the ¹³C- and ¹⁵N-labeled Glycine. Glycine is an inhibitory neurotransmitter in the CNS and also acts as a co-agonist along with glutamate, facilitating an excitatory potential at the glutaminergic N-methyl-D-aspartic acid (NMDA) receptors.

HY-Y1039S1

1-Stearoyl-rac-glycerol-d₃₅		99.91%
1-Stearoyl-rac-glycerol-d₃₅ is the deuterium labeled 1-Stearoyl-rac-glycerol.

HY-W012889S

DL-Valine-d₈		99.96%
DL-Valine-d₈ is the deuterium labeled DL-Valine.

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