2. Signaling Pathways
  3. Metabolic Enzyme/Protease
  4. Transglutaminase
  5. TGM2 Isoform
  6. TGM2 Inhibitor

TGM2 Inhibitor

TGM2 Inhibitors (3):

Cat. No. Product Name Effect Purity
  • HY-128595
    MT-4
    		Inhibitor 99.84%
    MT-4 is a derivative of a tissue transglutaminase (TG2) inhibitor. MT-4 targets the complex of TG2 and fibronectin (FN) (TG2/FN) and inhibits the adhesion of tumor cells to the matrix. MT-4 inhibits the adhesion of ovarian cancer (OC) cells to the peritoneum and increases the sensitivity of OC cells to paclitaxel.
  • HY-177133
    Suvigletistat
    		Inhibitor 99.82%
    Suvigletistat is a Transglutaminase 2 (TG2) inhibitor with an IC50 <0.5 μM. Suvigletistat can be used for the research of inflammatory disorders.
  • HY-181732
    PROTAC TG2 Degrader-3
    		Inhibitor
    PROTAC TG2 Degrader-3 is a TG2 (TGM2) PROTAC degrader. PROTAC TG2 Degrader-3 inhibits the adhesion and migration of ovarian cancer cells. PROTAC TG2 Degrader-3 can be used for the research of ovarian cancer.