Suvigletistat
Based on 1 Customer Validation
Suvigletistat is a Transglutaminase 2 (TG2) inhibitor with an IC50 <0.5 μM. Suvigletistat can be used for the research of inflammatory disorders.
For research use only. We do not sell to patients.
- Purity: 99.82%
- CAS No.: 2410912-75-1
- Formula: C28H36N6O5
- Molecular Weight:536.62
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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TGM2 <0.5 μM (IC50) |
Suvigletistat (Compound 2) inhibits TG2 with an IC50 < 0.5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2410912-75-1
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Appearance Solid
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Molecular Weight 536.62
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Formula C28H36N6O5
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Color White to off-white
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SMILES
CN(C)C(/C=C/CC[C@H](NC(OC)=O)C(NC1=CC=CN(CC2=NC3=CC=CC(CC(C)C)=C3N2)C1=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : ≥ 100 mg/mL (186.35 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.8635 mL | 9.3176 mL | 18.6352 mL | 46.5879 mL |
| 5 mM | 0.3727 mL | 1.8635 mL | 3.7270 mL | 9.3176 mL | |
| 10 mM | 0.1864 mL | 0.9318 mL | 1.8635 mL | 4.6588 mL | |
| 15 mM | 0.1242 mL | 0.6212 mL | 1.2423 mL | 3.1059 mL | |
| 20 mM | 0.0932 mL | 0.4659 mL | 0.9318 mL | 2.3294 mL | |
| 25 mM | 0.0745 mL | 0.3727 mL | 0.7454 mL | 1.8635 mL | |
| 30 mM | 0.0621 mL | 0.3106 mL | 0.6212 mL | 1.5529 mL | |
| 40 mM | 0.0466 mL | 0.2329 mL | 0.4659 mL | 1.1647 mL | |
| 50 mM | 0.0373 mL | 0.1864 mL | 0.3727 mL | 0.9318 mL | |
| 60 mM | 0.0311 mL | 0.1553 mL | 0.3106 mL | 0.7765 mL | |
| 80 mM | 0.0233 mL | 0.1165 mL | 0.2329 mL | 0.5823 mL | |
| 100 mM | 0.0186 mL | 0.0932 mL | 0.1864 mL | 0.4659 mL |
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