1. GPCR/G Protein
  2. Apelin Receptor (APJ)
  3. (Ala13)-Apelin-13

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway.

For research use only. We do not sell to patients.

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(Ala13)-Apelin-13 Chemical Structure

(Ala13)-Apelin-13 Chemical Structure

CAS No. : 568565-11-7

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Description

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway[1].

In Vivo

(Ala13)-Apelin-13 (1-300 pmol/60 nl; microinjected into the DVC) decreases gastric tone and motility in a dose-dependent manner in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 250-300 g, Sprague-Dawley rats[1]
Dosage: 1-300 pmol/60 nl
Administration: Microinjected into the DVC (dorsal vagal complex (DVC)
Result: Decreased gastric tone and motility in a dose-dependent manner with D50 ≈ 27 pmol for both antrum and corpus.
Molecular Weight

1474.73

Formula

C63H107N23O16S

CAS No.
Sequence

Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala

Sequence Shortening

QRPRLSHKGPMPA

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Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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(Ala13)-Apelin-13 Related Classifications

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(Ala13)-Apelin-13
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HY-P3162
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