2. GPCR/G Protein
  3. Apelin Receptor (APJ)
  4. (Ala13)-Apelin-13

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway.

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(Ala13)-Apelin-13

(Ala13)-Apelin-13 Estructura química

No. CAS : 568565-11-7

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(Ala13)-Apelin-13 Related Antibodies

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Descripciòn

(Ala13)-Apelin-13 is a potent apelin receptors (APJ) antagonist. (Ala13)-Apelin-13 inhibits gastric motility through vagal cholinergic pathway[1].

In Vivo

(Ala13)-Apelin-13 (1-300 pmol/60 nl; microinjected into the DVC) decreases gastric tone and motility in a dose-dependent manner in rats[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: 250-300 g, Sprague-Dawley rats[1]
Dosage: 1-300 pmol/60 nl
Administration: Microinjected into the DVC (dorsal vagal complex (DVC)
Result: Decreased gastric tone and motility in a dose-dependent manner with D50 ≈ 27 pmol for both antrum and corpus.
Peso molecular

1474.73

Fòrmula

C63H107N23O16S
No. CAS
Sequence

Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Ala
Sequence Shortening

QRPRLSHKGPMPA
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Room temperature in continental US; may vary elsewhere.
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(Ala13)-Apelin-13 Related Classifications

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Keywords:

(Ala13)-Apelin-13568565-11-7Apelin Receptor (APJ)gastric tonemotilitycholinergic pathwayvagusdorsal vagal complexInhibitorinhibitorinhibit

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Nombre del producto:
(Ala13)-Apelin-13
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HY-P3162
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