1. Peptides
  2. Apelin-12

Apelin-12 

Cat. No.: HY-P2537
Handling Instructions

Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

Apelin-12 Chemical Structure

Apelin-12 Chemical Structure

CAS No. : 229961-08-4

Size Stock
100 mg   Get quote  
250 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

Apelin-12 is one of the most potent C-terminal fragments of the polypeptide that possesses a high affinity to orphan receptor APJ receptor. Apelin-12 is involved in the regulation of body fluid homeostasis and in the central control of feeding. Apelin-12 blocks HIV-1 entry through APJ receptor. Apelin-12 exerts neuroprotective effect[1][2][3].

In Vitro

Apelin-12 (A12) exerts neuroprotective effect against ischemia-reperfusion injury by inhibiting JNK and p38 MAPK signaling pathway in mouse[1].
Administration of exogenous A12 reduces arterial blood pressure in anesthetized rats due to activation of endothelial nitric oxide synthase and exerts a positive inotropic action in failing myocardium of rodents[2].
Apelin-12 stimulates acid secretion through an increase of histamine release in rat stomachs[4].

Molecular Weight

1422.70

Formula

C₆₄H₁₀₃N₂₁O₁₄S

CAS No.

229961-08-4

Sequence Shortening

RPRLSHKGPMPF

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Apelin-12Apelin12Apelin 12OthersorphanreceptorbodyfluidhomeostasisneuroprotectivehistamineacidsecretionInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Department *

 

Requested quantity *

Country or Region *

     

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
Apelin-12
Cat. No.:
HY-P2537
Quantity:
MCE Japan Authorized Agent: