Antibacterial agent 227
Antibacterial agent 227 (Compd 29) is a SerRS (Seryl-tRNA synthetase) inhibitor. Antibacterial agent 227 has a significant inhibitory effect on the growth of planktonic and biofilm culture of Staphylococcus aureus 25923 with MIC (minimum inhibitory concentration) value of 32 µg/ml. Antibacterial agent 227 can be proposed as effective antiseptic toward multidrug-resistant biofilm-forming S. aureus isolates.
For research use only. We do not sell to patients.
- CAS No.: 301304-67-6
- Formula: C12H13N5O3
- Molecular Weight:275.26
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Seryl-tRNA synthetase (SerRS)
Antibacterial agent 227 (0-32 µg/ml) has a significant inhibitory effect on the growth of planktonic culture of S. aureus 25923, but does not reveal antibacterial activity toward gram-negative bacterium E. coli[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 301304-67-6
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Molecular Weight 275.26
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Formula C12H13N5O3
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SMILES
O=C(N1)C(C)=NN=C1N/N=C/C2=C(O)C(OC)=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)