CD39 Antibody (YA4060)
(Synonyms: ENTPD1; SPG64; ATPDase; NTPDase-1)CD39 Antibody (YA4060) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD39.
-
Host:
Mouse
-
Isotype:
IgG1
-
Application:
WB, ELISA
-
Reactivity :
Human
-
Formulation:
Supplied in PBS with 0.05% sodium azide
-
Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
ELISA
ELISA: Enzyme Linked Immunosorbent Assay
|
|---|---|---|
| Dilution Ratio | 1:500-1:2000 | 1:10000 |
Product Details
CD39 Antibody (YA4060) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to CD39.
-
Host Mouse
-
Clonality Monoclonal
-
Species ReactivityHuman
-
Observed Molecular WeightObserved band size: 70 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
-
Calculated Molecular Weight Predicted band size: 58 kDa
Purified recombinant fragment of human CD39 (AA: extra 38-179) expressed in E. Coli.
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
-
Appearance
Liquid
-
Formulation
Supplied in PBS with 0.05% sodium azide
-
Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
-
Shipping
Shipping with blue ice.
Background
-
Function
CD39 catalyzes the hydrolysis of both di- and triphosphate nucleotides (NDPs and NTPs) and hydrolyze NTPs to nucleotide monophosphates (NMPs) in two distinct successive phosphate-releasing steps, with NDPs as intermediates and participates in the regulation of extracellular levels of nucleotides (Probable). By hydrolyzing proinflammatory ATP and platelet-activating ADP to AMP, it blocks platelet aggregation and supports blood flow[1][2][3][4].
-
Subcellular Localization
Membrane; Multi-pass membrane protein; Membrane, caveola
-
Expression
Tissue_specificity:It is primarily expressed on activated lymphocytes (PubMed:7930580) . It is also expressed in endothelial tissues (PubMed:8955160) . It is highly expressed in the placenta, lungs, skeletal muscle, and kidneys (PubMed:8955160) . -
Isoforms & Post-Translational Modification
P49961 has 6 isomers: P49961-1: 57965 Da (predicted); P49961-2: 58706 Da (predicted); P49961-3: 34175 Da (predicted); P49961-4: 42731 Da (predicted); P49961-5: 46180 Da (predicted); P49961-6: 59325 Da (predicted).
N-glycosylated;The N-terminus is blocked;Palmitoylated on Cys-13; which is required for caveola targeting -
Subunit
Homodimer; disulfide-linked
-
SwissProt ID
-
Synonyms
ENTPD1; SPG64; ATPDase; NTPDase-1
Documentation
Powered by Bioz
