CDC25 Antibody (YA2450)
(Synonyms: GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1)CDC25 Antibody (YA2450) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC25.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
|
|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
CDC25 Antibody (YA2450) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CDC25.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityRat
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Observed Molecular WeightObserved band size: 145 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 145 kDa
Entrez Gene: 192213 Rat
SwissProt: P28818 Rat
A synthetic peptide of human CDC25
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
CDC25 promotes the exchange of Ras-bound GDP by GTP
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Isoforms & Post-Translational Modification
Q13972 has 3 isomers: Q13972-1: 145234 Da (predicted); Q13972-2: 55489 Da (predicted); Q13972-3: 143218 Da (predicted).
Phosphorylated by PLK2, leading to ubiquitination and degradation by the proteasome;Ubiquitinated and degraded following phosphorylation by PLK2;Phosphorylated by SRC and LCK. Phosphorylation by LCK increases its capacity to stimulate the GDP/GTP exchange on Ras, whereas its phosphorylation by SRC seems not to have an effect on stimulation activity -
Subunit
Homooligomer and heterooligomer with RASGRF2.
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SwissProt ID
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Synonyms
GNRP; GRF1; CDC25; GRF55; CDC25L; H-GRF55; PP13187; ras-GRF1
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Research Field
Signal Transduction
Documentation
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