Complex III Subunit 7 Antibody (YA2358)
(Synonyms: QPC; QCR7; QP-C; UQBC; UQBP; UQPC; UQCR6; MC3DN3)Complex III Subunit 7 Antibody (YA2358) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Complex III Subunit 7.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IP
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Reactivity :
Human, Rat
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Formulation:
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IP
IP: Immunoprecipitation
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|---|---|---|---|
| Dilution Ratio | 1:500-1:1000 | 1:50-1:100 | 1:20 |
Product Details
Complex III Subunit 7 Antibody (YA2358) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Complex III Subunit 7.
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Host Rabbit
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Clonality Recombinant, Monoclonal
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Species ReactivityHuman, Rat
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Observed Molecular WeightObserved band size: 14 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 14 kDa
Entrez Gene: 7381 Human ; 67530 Mouse ; 362897 Rat
SwissProt: P14927 Human ; Q9D855 Mouse ;
OMIM: 615158 Human
Recombinant protein of human UQCRB aa2-111.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Complex III Subunit 7 component of the ubiquinol-cytochrome c oxidoreductase, a multisubunit transmembrane complex that is part of the mitochondrial electron transport chain which drives oxidative phosphorylation. The respiratory chain contains 3 multisubunit complexes succinate dehydrogenase (complex II, CII), ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII) and cytochrome c oxidase (complex IV, CIV), that cooperate to transfer electrons derived from NADH and succinate to molecular oxygen, creating an electrochemical gradient over the inner membrane that drives transmembrane transport and the ATP synthase. The cytochrome b-c1 complex catalyzes electron transfer from ubiquinol to cytochrome c, linking this redox reaction to translocation of protons across the mitochondrial inner membrane, with protons being carried across the membrane as hydrogens on the quinol. In the process called Q cycle, 2 protons are consumed from the matrix, 4 protons are released into the intermembrane space and 2 electrons are passed to cytochrome c
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Subcellular Localization
Mitochondrion inner membrane; Peripheral membrane protein; Matrix side
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Isoforms & Post-Translational Modification
P14927 has 2 isomers: P14927-1: 13530 Da (predicted); P14927-2: 16267 Da (predicted).
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Subunit
Component of the ubiquinol-cytochrome c oxidoreductase (cytochrome b-c1 complex, complex III, CIII), a multisubunit enzyme composed of 11 subunits.
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SwissProt ID
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Synonyms
QPC; QCR7; QP-C; UQBC; UQBP; UQPC; UQCR6; MC3DN3
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Research Field
Cardiovascular
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