DLL4 Antibody (YA7088)

Cat. No.: HY-P87400: Data Sheet User Guide for Antibodies
FAQs
Technical Support

DLL4 Antibody (YA7088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DLL4.

For research use only. We do not sell to patients.

Size	Price	Stock
20 μL		Ask For Quote & Lead Time
50 μL		Ask For Quote & Lead Time
100 μL		Ask For Quote & Lead Time

* Please select Quantity before adding items.

WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

DLL4 Antibody (YA7088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DLL4.

Host

Mouse

Clonality

Monoclonal

Molecular Weight

Predicted band size: 74.6kDa;

Species Reactivity

Human

SwissProt ID

Q9NR61

Immunogen

Purified recombinant fragment of human DLL4 expressed in E. Coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:200-1000
ELISA ELISA: Enzyme Linked Immunosorbent Assay	1:10000

Sensitivity	Endogenous	Purity	affinity purified.
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG1

Appearance

Liquid

Formulation

Supplied in PBS with 0.05% sodium azide.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in the Notch signaling pathway as Notch ligand (PubMed:11134954). Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting (PubMed:20616313). Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types (By similarity). During spinal cord neurogenesis, inhibits V2a interneuron fate (PubMed:17728344)

Subcellular Localization：Cell membrane

Expression：
Tissue_Specificity: Expressed in vascular endothelium

Isoforms & Post-Translational Modification：Q9NR61: 685 amino acids, molecular weight 74605 Da.

Subunit：Interacts with NOTCH4

Database

SwissProt: Q9NR61 Human

Documentation

User Guide for Antibodies (1077 KB)