DLL4 Antibody (YA7088)
DLL4 Antibody (YA7088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DLL4.
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Host:
Mouse
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Isotype:
IgG1
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Application:
IHC-P, ELISA
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Reactivity :
Human
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Formulation:
Supplied in PBS with 0.05% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ELISA
ELISA: Enzyme Linked Immunosorbent Assay
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|---|---|---|
| Dilution Ratio | 1:200-1000 | 1:10000 |
Product Details
DLL4 Antibody (YA7088) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to DLL4.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 74.6kDa;
SwissProt: Q9NR61 Human
Purified recombinant fragment of human DLL4 expressed in E. Coli.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG1
Product Properties
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Appearance
Liquid
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Formulation
Supplied in PBS with 0.05% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
DLL4 is involved in the Notch signaling pathway as Notch ligand. Activates NOTCH1 and NOTCH4. Involved in angiogenesis; negatively regulates endothelial cell proliferation and migration and angiogenic sprouting. Essential for retinal progenitor proliferation. Required for suppressing rod fates in late retinal progenitors as well as for proper generation of other retinal cell types. During spinal cord neurogenesis, inhibits V2a interneuron fate[1][2][3].
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: Expressed in vascular endothelium -
Isoforms & Post-Translational Modification
Q9NR61: 685 amino acids, molecular weight 74605 Da.
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Subunit
Interacts with NOTCH4
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SwissProt ID
Documentation
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