EPS8L2 Antibody
(Synonyms: EPS8R2, PP13181, EPS8L2, Epidermal growth factor receptor kinase substrate 8-like protein 2, EPS8-like protein 2, Epidermal growth factor receptor pathway substrate 8-related protein 2, EPS8-related protein 2)EPS8L2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to EPS8L2.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
EPS8L2 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to EPS8L2.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 95 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 80 kDa
Synthetic peptide corresponding to the N-term region of human EPS8L2.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
EPS8L2 stimulates guanine exchange activity of SOS1. May play a role in membrane ruffling and remodeling of the actin cytoskeleton. In the cochlea, is required for stereocilia maintenance in adult hair cells (By similarity)
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Subcellular Localization
Cytoplasm; Cell projection, stereocilium
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Expression
Tissue_Specificity: Detected in fibroblasts and placenta. -
Isoforms & Post-Translational Modification
EPS8L2 has 3 isoforms, Q9H6S3-1: amino acid length is 715, molecular weight is 80621 Da (predicted); Q9H6S3-2: amino acid length is 327, molecular weight is 37113 Da (predicted); Q9H6S3-3: amino acid length is 731, molecular weight is 82323 Da (predicted).EPS8L2 存在 3 个异构体，Q9H6S3-1：氨基酸个数为 715 个，分子量为 80621 Da (预测)；Q9H6S3-2：氨基酸个数为 327 个，分子量为 37113 Da (预测)；Q9H6S3-3：氨基酸个数为 731 个，分子量为 82323 Da (预测)。
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Subunit
Interacts with ABI1.
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SwissProt ID
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Synonyms
EPS8R2, PP13181, EPS8L2, Epidermal growth factor receptor kinase substrate 8-like protein 2, EPS8-like protein 2, Epidermal growth factor receptor pathway substrate 8-related protein 2, EPS8-related protein 2
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