MUM1 Antibody (YA7738)

Art. -Nr.: HY-P88053: Data Sheet User Guide for Antibodies
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Technical Support

MUM1 Antibody (YA7738) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUM1.

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Größe		Verfügbarkeit
50 μL		Angebot einholen
100 μL		Angebot einholen

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Beschreibung

Beschreibung

MUM1 Antibody (YA7738) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUM1.

Host

Mouse

Clonality

Monoclonal

Molekulargewicht

Predicted band size: 79 kDa;

Species Reactivity

Human

SwissProt ID

Q2TAK8

Immunogen

Full length native Protein

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:100-500
IHC-F IHC-F: Immunohistochemistry-Frozen	1:100-500
IF-Tissue IF-Tissue: Immunofluorescence-Tissue	1:100-500

Sensitivity	Endogenous	Reinheit	affinity purified by Protein G
Conjugation	Non-conjugated	Modification	Unmodified
Isotype	IgG2a

Appearance

Liquid

Formulation

Supplied in 10mM TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Versand

Shipping with blue ice.

Background

Function：Involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage

Subcellular Localization：Nucleus

Isoforms & Post-Translational Modification：Q2TAK8 has three isomers: Q2TAK8-1: 78636 Da (predicted); Q2TAK8-2: 70733 Da (predicted); Q2TAK8-3: 80700 Da (predicted).

Subunit：Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status

Dokumentation

User Guide for Antibodies (1077 KB)