MUM1 Antibody (YA7738)
(Synonyms: EXPAND1, MUM1, PWWP3A, PWWP domain-containing DNA repair factor 3A, Mutated melanoma-associated antigen 1, PWWP domain-containing protein MUM1, Protein expandere, MUM-1)MUM1 Antibody (YA7738) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUM1.
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Host:
Mouse
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Isotype:
IgG
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Application:
IHC-P, IHC-F, IF-Tissue
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Reactivity :
Human
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Formulation:
Supplied in 10mM TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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|---|---|---|---|
| Dilution Ratio | 1:100-500 | 1:100-500 | 1:100-500 |
Product Details
MUM1 Antibody (YA7738) is a Mouse-derived and non-conjugated IgG2a monoclonal antibody, targeting to MUM1.
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Host Mouse
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Clonality Monoclonal
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Species ReactivityHuman
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Calculated Molecular Weight Predicted band size: 79 kDa;
Full length native Protein
Endogenous
affinity purified by Protein G
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in 10mM TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
MUM1 is involved in the DNA damage response pathway by contributing to the maintenance of chromatin architecture. Recruited to the vicinity of DNA breaks by TP53BP1 and plays an accessory role to facilitate damage-induced chromatin changes and promoting chromatin relaxation. Required for efficient DNA repair and cell survival following DNA damage
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
Q2TAK8 has three isomers: Q2TAK8-1: 78636 Da (predicted); Q2TAK8-2: 70733 Da (predicted); Q2TAK8-3: 80700 Da (predicted).
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Subunit
Interacts with TP53BP1 (via BRCT domain); the interaction is not dependent on its phosphorylation status
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SwissProt ID
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Synonyms
EXPAND1, MUM1, PWWP3A, PWWP domain-containing DNA repair factor 3A, Mutated melanoma-associated antigen 1, PWWP domain-containing protein MUM1, Protein expandere, MUM-1
Documentation
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