PRELID1 Antibody (YA8075)(PBS only)

Cat. No.: HY-P88391A: Data Sheet User Guide for Antibodies
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PRELID1 Antibody (YA8075) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PRELID1.

For research use only. We do not sell to patients.

Size		Stock
50 μL		Get quote
100 μL		Get quote

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WB: Western Blot;
IHC-P: Immunohistochemistry-Paraffin;
IHC-F: Immunohistochemistry-Frozen;
ICC/IF: Immunocytochemistry/Immunofluorescence;
IF-Tissue: Immunofluorescence-Tissue;
mIHC: Multiplex Immunohistochemical;
IP: Immunoprecipitation;
ChIP: Chromatin Immunoprecipitation;
FC: Flow Cytometry;
ELISA: Enzyme Linked Immunosorbent Assay

Product Detail
Background
Documentation

Description

PRELID1 Antibody (YA8075) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to PRELID1.

Host

Mouse

Molecular Weight

Predicted band size: 25 kDa

Species Reactivity

Human, Mouse, Rat

SwissProt ID

Q9Y255

Immunogen

Human recombinant protein fragment corresponding to amino acids 36-219 of human PRELID1 produced in E.coli.

Application &
Dilution Ratio

Application	Dilution Ratio
IHC-P IHC-P: Immunohistochemistry-Paraffin	1:500-800

Purity	Affinity purified	Conjugation	Non-conjugated
Isotype	IgG2b

Appearance

Liquid

Formulation

Supplied in PBS, pH 7.4.

Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

Shipping

Shipping with blue ice.

Background

Function：Involved in the modulation of the mitochondrial apoptotic pathway by ensuring the accumulation of cardiolipin (CL) in mitochondrial membranes. In vitro, the TRIAP1:PRELID1 complex mediates the transfer of phosphatidic acid (PA) between liposomes and probably functions as a PA transporter across the mitochondrion intermembrane space to provide PA for CL synthesis in the inner membrane. Regulates the mitochondrial apoptotic pathway in primary Th cells. Regulates Th cell differentiation by down-regulating STAT6 thereby reducing IL-4-induced Th2 cell number. May be important for the development of vital and immunocompetent organs

Subcellular Localization：Mitochondrion,Mitochondrion intermembrane space

Expression：
Tissue_Specificity: Highly expressed in fetal liver; less expressed in fetal brain, lung, and kidney. At the adult stage, expression is drastically reduced in the liver but highly expressed in the spleen, brain, lung, lymph nodes and peripheral blood leukocytes
Induction: Up-regulated in response to activation in primary T helper cells

Isoforms & Post-Translational Modification：Q9Y255 has two isomers: Q9Y255-1: 25181 Da (predicted); Q9Y255-2: 24068 Da (predicted).

Subunit：Forms a complex with TRIAP1 in the mitochondrion intermembrane space

Synonyms

CGI-106; PRELI; PX19; SBBI12

Documentation

User Guide for Antibodies (1077 KB)