PRKAR1 Antibody (YA7323)
PRKAR1 Antibody (YA7323) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PRKAR1.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, IHC-F, IF-Tissue, ICC/IF
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Reactivity :
Human
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Formulation:
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Conjugation:
Non-conjugated
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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IHC-F
IHC-F: Immunohistochemistry-Frozen
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IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:100-200 | 1:50-200 | 1:50-200 |
Product Details
PRKAR1 Antibody (YA7323) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to PRKAR1.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman Predicted Reactivity: Mouse,RatNote: The predicted reactivity is for reference only and should not be considered a guarantee of product performance.
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Observed Molecular WeightObserved band size: 48 kDaNote: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 43 kDa
A synthesized peptide derived from human PRKAR1A
Endogenous
affinity purified by Protein A
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Liquid
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Formulation
Supplied in 10mM phosphate buffered saline(pH 7.4) with 150mM sodium chloride, 0.05% BSA, 0.02% Proclin300 and 50% glycerol.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
PRKAR1 is a Regulatory subunit of the cAMP-dependent protein kinases involved in cAMP signaling in cells
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Subcellular Localization
Cell membrane
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Expression
Tissue_Specificity: Four types of regulatory chains are found: I-alpha, I-beta, II-alpha, and II-beta. Their expression varies among tissues and is in some cases constitutive and in others inducible -
Isoforms & Post-Translational Modification
P10644 has two isomers: P10644-1: 42982 Da (predicted); P10644-2: 38003 Da (predicted).
The pseudophosphorylation site binds to the substrate-binding region of the catalytic chain, resulting in the inhibition of its activity -
Subunit
The inactive holoenzyme is composed of two regulatory chains and two catalytic chains
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SwissProt ID
Documentation