Rad52 Antibody (YA2716)
(Synonyms: Rad52; RAD52 homolog)
Based on 1 Customer Validation
Rad52 Antibody (YA2716) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rad52.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB
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Reactivity :
Human
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Formulation:
Supplied in rabbit IgG in PBS(pH 7.4), 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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|---|---|
| Dilution Ratio | 1:500-1:1000 |
Product Details
Rad52 Antibody (YA2716) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Rad52.
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Host Rabbit
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Clonality Recombinant,Monoclonal
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Species ReactivityHuman
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Observed Molecular WeightObserved band size: 46 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 46 kDa
A synthesized peptide derived from human RAD52 aa380-418.
Endogenous
Affinity Purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in rabbit IgG in PBS(pH 7.4), 150mM sodium chloride, 0.05% BSA, 0.02% sodium azide and 50% glycerol.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Rad52 is involved in double-stranded break repair. Plays a central role in genetic recombination and DNA repair by promoting the annealing of complementary single-stranded DNA and by stimulation of the RAD51 recombinase
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
P43351 has 4 isomers: P43351-1: 46169 Da (predicted); P43351-2: 24540 Da (predicted); P43351-3: 15350 Da (predicted); P43351-4: 12943 Da (predicted).
Phosphorylated upon DNA damage by ABL1, and probably by ATM or ATR -
Subunit
The full-length protein forms heptameric rings (PubMed:12191481). Interacts with ABL1 (PubMed:12379650). Interacts with RPA2; the interaction is direct and associates RAD52 with the RPA complex (PubMed:8702565). Interacts with RAD51AP1 (PubMed:31400850)
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SwissProt ID
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Synonyms
Rad52; RAD52 homolog
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Research Field
Epigenetics and Nuclear Signaling
Documentation
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