Septin 6 Antibody
(Synonyms: KIAA0128, SEP2, SEPT6, SEPTIN6, Septin-6)Septin 6 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Septin 6.
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Host:
Rabbit
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Isotype:
IgG
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Application:
WB, IHC-P, ICC/IF
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Reactivity :
Human, Mouse, Rat
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Formulation:
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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IHC-P
IHC-P: Immunohistochemistry-Paraffin
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
|---|---|---|---|
| Dilution Ratio | 1:1000-2000 | 1:100-200 | 1:50-200 |
Product Details
Septin 6 Antibody is a Rabbit-derived and non-conjugated IgG Polyclonal antibody, targeting to Septin 6.
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Host Rabbit
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Clonality Polyclonal
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Species ReactivityHuman, Mouse, Rat
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Observed Molecular WeightObserved band size: 50 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
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Calculated Molecular Weight Predicted band size: 49 kDa
Synthetic peptide corresponding to the center region of human Septin 6.
Endogenous
affinity purified.
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS (pH 7.4), containing 30% glycerol, and 0.01% sodium azide.
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Storage & Stability
Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
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Shipping
Shipping with blue ice.
Background
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Function
Septin 6 is a Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Involved in cytokinesis. May play a role in HCV RNA replication. Forms a filamentous structure with SEPTIN12, SEPTIN6, SEPTIN2 and probably SEPTIN4 at the sperm annulus which is required for the structural integrity and motility of the sperm tail during postmeiotic differentiation[1].
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Subcellular Localization
Cytoplasm; Cytoplasm, cytoskeleton, spindle; Chromosome, centromere, kinetochore; Cleavage furrow; Midbody; Cell projection, cilium, flagellum
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Expression
Tissue_Specificity: Widely expressed. -
Isoforms & Post-Translational Modification
Septin 6 has 4 isoforms, Q14141-1: amino acid length is 434, molecular weight is 49717 Da (predicted); Q14141-2: amino acid length is 427, molecular weight is 48873 Da (predicted); Q14141-3: amino acid length is 267, molecular weight is 29584 Da (predicted); Q14141-4: amino acid length is 429, molecular weight is 49167 Da (predicted).
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Subunit
Septins polymerize into heterooligomeric protein complexes that form filaments, and associate with cellular membranes, actin filaments and microtubules.
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SwissProt ID
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Synonyms
KIAA0128, SEP2, SEPT6, SEPTIN6, Septin-6
Documentation
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