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Tissue Factor Pathway Inhibitor Antibody (YA3272)

(Synonyms: EPI; TFI; LACI; TFPI1)

Tissue Factor Pathway Inhibitor Antibody (YA3272) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tissue Factor Pathway Inhibitor.

For research use only. We do not sell to patients.
  • Host:

    Rabbit

  • Isotype:

    IgG

  • Application:

    WB, IP

  • Reactivity :

    Human

  • Formulation:

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Conjugation:
    Non-conjugated
  • Tissue Factor Pathway Inhibitor Antibody (YA3272) Product Image
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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Applications

Application
WB Info
WB: Western Blot
IP Info
IP: Immunoprecipitation
Dilution Ratio 1:500-1:1000 1:20

Product Details

Description

Tissue Factor Pathway Inhibitor Antibody (YA3272) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Tissue Factor Pathway Inhibitor.

  • Host Rabbit
  • Clonality Recombinant, Monoclonal
  • Species Reactivity
    Human
  • Observed Molecular Weight
    Observed band size: 40-55 kDa Info
    Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
  • Calculated Molecular Weight Predicted band size: 35 kDa
Species Reactivity Database

Entrez Gene: 7035 Human

SwissProt: P10646 Human

Immunogen

Recombinant protein of human TFPI

Sensitivity

Endogenous

Purification

Affinity Purified

Conjugation

Non-conjugated

Modification

Unmodified

Isotype

IgG

Product Properties

  • Appearance

    Liquid

  • Formulation

    Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA

  • Storage & Stability

    Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.

  • Shipping

    Shipping with blue ice.

Background

  • Function

    Tissue Factor Pathway Inhibitor inhibits factor X (X(a)) directly and, in a Xa-dependent way, inhibits VIIa/tissue factor activity, presumably by forming a quaternary Xa/LACI/VIIa/TF complex. It possesses an antithrombotic action and also the ability to associate with lipoproteins in plasma

  • Subcellular Localization

    Secreted; Microsome membrane; Lipid-anchor, GPI-anchor

  • Expression


    Tissue_specificity:Mostly in endothelial cells

  • Isoforms & Post-Translational Modification

    P10646 has 2 isomers: P10646-1: 35015 Da (predicted); P10646-2: 28653 Da (predicted).
    O-glycosylated

  • SwissProt ID

    P10646

  • Gene ID
    7035 [NCBI]
  • Synonyms

    EPI; TFI; LACI; TFPI1

  • Research Field

    Cardiovascular

Tissue Factor Pathway Inhibitor Antibody (YA3272) Related Classifications

MOQ
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100 mg

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Measured by its ability to inhibit anti-CD3-induced proliferation of stimulated CTLL-2 mouse cytotoxic T cells. The ED50 this effect is 0.8023 μg/ml, corresponding to a specific activity is 1246.42 units/mg.

Assay Types
  • Tissue Factor Pathway Inhibitor Antibody (YA3272) Product Image
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  • Tissue Factor Pathway Inhibitor Antibody (YA3272) Product Image