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  3. Primary Antibodies
  4. Monoclonal Antibodies Recombinant Antibodies
  5. Transmembrane Protein 85 Antibody (YA2225)

Transmembrane Protein 85 Antibody (YA2225)

Cat. No.: HY-P82480
User Guide for Antibodies Technical Support

Transmembrane Protein 85 Antibody (YA2225) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transmembrane Protein 85.

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사이즈 가격 재고 수량
20 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
50 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
100 μL 견적 받기 2 - 3 Weeks 1 - 2 Weeks 3 - 4 Weeks 2 - 3 weeks
250 μL   견적 받기  
Synthetic products have potential research and development risk.
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Top Publications Citing Use of Products
  • WB: Western Blot;
  • IHC-P: Immunohistochemistry-Paraffin;
  • IHC-F: Immunohistochemistry-Frozen;
  • ICC/IF: Immunocytochemistry/Immunofluorescence;
  • IF-Tissue: Immunofluorescence-Tissue;
  • mIHC: Multiplex Immunohistochemical;
  • IP: Immunoprecipitation;
  • ChIP: Chromatin Immunoprecipitation;
  • FC: Flow Cytometry;
  • ELISA: Enzyme Linked Immunosorbent Assay

  • Product Detail

  • Background

  • 제품 설명

제품 설명

Transmembrane Protein 85 Antibody (YA2225) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Transmembrane Protein 85.
Host

Rabbit
Clonality

Recombinant, Monoclonal
분자량
Predicted band size: 20 kDa;
Observed band size: 20 kDa
Note: Due to possible protein modifications or aggregation, the molecular weight should be confirmed by actual measurement, and the predicted value is for reference only.
Species Reactivity
Human, Mouse, Rat, Hamster
SwissProt ID
Gene ID
Immunogen

A synthetic peptide of human TMEM85 aa42-55.
Application &
Dilution Ratio
Application Dilution Ratio
WB
WB: Western Blot
1:500-1:1000
IP
IP: Immunoprecipitation
1:20
Sensitivity Endogenous Purity Affinity Purified
Conjugation Non-conjugated Modification Unmodified
Isotype IgG  
Appearance

Liquid
Formulation

Supplied in 50mM Tris-Glycine(pH 7.4), 0.15M NaCl, 40% Glycerol, 0.01% Sodium azide and 0.05% BSA
Storage & Stability

Stored at -20°C for 1 year. Avoid repeated freeze / thaw cycles.
선적

Shipping with blue ice.
Background
Function：Part of the endoplasmic reticulum membrane protein complex (EMC) that enables the energy-independent insertion into endoplasmic reticulum membranes of newly synthesized membrane proteins (PubMed:29242231, PubMed:29809151, PubMed:30415835, PubMed:32439656, PubMed:32459176). Preferentially accommodates proteins with transmembrane domains that are weakly hydrophobic or contain destabilizing features such as charged and aromatic residues (PubMed:29242231, PubMed:29809151, PubMed:30415835). Involved in the cotranslational insertion of multi-pass membrane proteins in which stop-transfer membrane-anchor sequences become ER membrane spanning helices (PubMed:29809151, PubMed:30415835). It is also required for the post-translational insertion of tail-anchored/TA proteins in endoplasmic reticulum membranes (PubMed:29242231, PubMed:29809151). By mediating the proper cotranslational insertion of N-terminal transmembrane domains in an N-exo topology, with translocated N-terminus in the lumen of the ER, controls the topology of multi-pass membrane proteins like the G protein-coupled receptors (PubMed:30415835). By regulating the insertion of various proteins in membranes, it is indirectly involved in many cellular processes (Probable)
Subcellular Localization：Endoplasmic reticulum membrane; Multi-pass membrane protein
Expression：
Tissue_specificity:Isoform 1 is expressed in brain and heart. Isoform 2 is expressed in heart
Isoforms & Post-Translational Modification：Q5J8M3 has 3 isomers: Q5J8M3-1: 20087 Da (predicted); Q5J8M3-2: 16745 Da (predicted); Q5J8M3-3: 15088 Da (predicted).
Subunit：Component of the ER membrane protein complex (EMC)
Database

Entrez Gene: 51234 Human ; 68032 Mouse ; 296049 Rat

SwissProt: Q5J8M3 Human ; Q9CZX9 Mouse ;

OMIM: 616245 Human

Research Field

Cell Biology
Synonyms
PIG17; TMEM85
각종 서류
User Guide for Antibodies (1077 KB)

Transmembrane Protein 85 Antibody (YA2225) Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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상품명:
Transmembrane Protein 85 Antibody (YA2225)
Cat. No.:
HY-P82480
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