TRAP95 Antibody (YA9290)
(Synonyms: DRIP92, THRAP5, MED16, Mediator of RNA polymerase II transcription subunit 16, Mediator complex subunit 16, Thyroid hormone receptor-associated protein 5, Thyroid hormone receptor-associated protein complex 95 kDa component, Vitamin D3 receptor-interacting protein complex 92 kDa component, Trap95)
Based on 1 Customer Validation
TRAP95 Antibody (YA9290) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TRAP95.
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Host:
Mouse
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Isotype:
IgG
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Application:
WB, ICC/IF, IF-Tissue, IP
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Reactivity :
human
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Formulation:
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Conjugation:
Non-conjugated
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
Applications
| Application |
WB
WB: Western Blot
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ICC/IF
ICC/IF: Immunocytochemistry/
Immunofluorescence |
IF-Tissue
IF-Tissue: Immunofluorescence-Tissue
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IP
IP: Immunoprecipitation
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|---|---|---|---|---|
| Dilution Ratio | 1:500-1000 | 1:50-500 | 1:50-500 | 1-2μg per 100-500μg Total protein |
Product Details
TRAP95 Antibody (YA9290) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to TRAP95.
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Host Mouse
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Species Reactivityhuman
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Calculated Molecular Weight Predicted band size: 97 kDa
OMIM: 604062
A synthesized peptide derived from human TRAP95.
Endogenous
Affinity purified
Non-conjugated
Unmodified
IgG
Product Properties
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Appearance
Solution
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Formulation
Supplied in PBS(pH7.4) containing 0.1% gelatin and < 0.1% sodium azide.
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Concentration
Batch-dependent, Please check the COA for the concentration of each lot. Check Lot Concentration
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Storage & Stability
Stored at 2-8°C for 1 year, do not freeze.
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Shipping
Shipping with blue ice.
Background
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Function
TRAP95 is a Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors
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Subcellular Localization
Nucleus
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Isoforms & Post-Translational Modification
TRAP95 has 5 isoforms, Q9Y2X0-1: amino acid length is 877, molecular weight is 96793 Da (predicted); Q9Y2X0-2: amino acid length is 841, molecular weight is 93029 Da (predicted); Q9Y2X0-3: amino acid length is 860, molecular weight is 95050 Da (predicted); Q9Y2X0-4: amino acid length is 751, molecular weight is 82179 Da (predicted); Q9Y2X0-5: amino acid length is 663, molecular weight is 72967 Da (predicted).
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Subunit
Component of the Mediator complex, which is composed of MED1, MED4, MED6, MED7, MED8, MED9, MED10, MED11, MED12, MED13, MED13L, MED14, MED15, MED16, MED17, MED18, MED19, MED20, MED21, MED22, MED23, MED24, MED25, MED26, MED27, MED29, MED30, MED31, CCNC, CDK8 and CDC2L6/CDK11.
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SwissProt ID
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Synonyms
DRIP92, THRAP5, MED16, Mediator of RNA polymerase II transcription subunit 16, Mediator complex subunit 16, Thyroid hormone receptor-associated protein 5, Thyroid hormone receptor-associated protein complex 95 kDa component, Vitamin D3 receptor-interacting protein complex 92 kDa component, Trap95
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