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Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. Antidepressant agent 1 also can be used to increase body temperature.

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Antidepressant agent 1 Chemical Structure

Antidepressant agent 1 Chemical Structure

CAS No. : 67411-41-0

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Antidepressant agent 1 Related Antibodies

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Description

Antidepressant agent 1 is a pyrazidole-halogeno-derivative with antidepressant effects. Antidepressant agent 1 also can be used to increase body temperature[1].

In Vitro

Antidepressant agent 1 (compound I) is prepared in 56% yields by reduction of compound II by NaBH4-AcOH. Compound II is obtained by condensation of compound III with BrCH2CH(OBu)2 followed by acid-catalyzed cyclization[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Antidepressant agent 1 Related Antibodies
Molecular Weight

319.24

Formula

C16H19BrN2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

CCN1CCN2C3=C(C4=C2C1CCC4)C=C(Br)C=C3
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 8.93 mg/mL (27.97 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1324 mL 15.6622 mL 31.3244 mL
5 mM 0.6265 mL 3.1324 mL 6.2649 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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C2

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V2

In Vivo Dissolution Calculator
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Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1324 mL 15.6622 mL 31.3244 mL 78.3110 mL
5 mM 0.6265 mL 3.1324 mL 6.2649 mL 15.6622 mL
10 mM 0.3132 mL 1.5662 mL 3.1324 mL 7.8311 mL
15 mM 0.2088 mL 1.0441 mL 2.0883 mL 5.2207 mL
20 mM 0.1566 mL 0.7831 mL 1.5662 mL 3.9155 mL
25 mM 0.1253 mL 0.6265 mL 1.2530 mL 3.1324 mL
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Antidepressant agent 1 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Antidepressant agent 167411-41-0Antidepressant agent1Antidepressant agent-1OthersPyrazidolehalogenoantidepressantNaBH4-AcOHtemperatureInhibitorinhibitorinhibit

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