1. Anti-infection
  2. Bacterial
  3. Antimicrobial agent-1

Antimicrobial agent-1 

Cat. No.: HY-146078
Handling Instructions

Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines.

For research use only. We do not sell to patients.

Antimicrobial agent-1 Chemical Structure

Antimicrobial agent-1 Chemical Structure

CAS No. : 2579696-45-8

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Description

Antimicrobial agent-1 (compound 6C) possesses potent activity against TolC mutant E. coli with an MIC value of 2 μg/mL. Antimicrobial agent-1 and Colistin exhibit synergistic activity against Gram-negative bacteria. Antimicrobial agent-1 has no cytotoxicity on mammalian cell lines, with MICs > 128 μg/mL in Caco-2 and Vero cell lines[1].

IC50 & Target

IC50: 2 μg/mL (TolC mutant E. coli)[1]

Molecular Weight

391.49

Formula

C22H21N3O2S

CAS No.
SMILES

CS(=O)(NC1=CC=CC(C2=NC3=CC=CC=C3N2CC4=CC=C(C)C=C4)=C1)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
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Product Name:
Antimicrobial agent-1
Cat. No.:
HY-146078
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