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  3. Arsenobetaine

Arsenobetaine is an organoarsenical and a compatible solute that has been found in various marine animals, such as lobsters and crabs, as well as terrestrial organisms, including earthworms and lichens. Arsenobetaine is protective against B. subtilis cell death induced by high osmolarity or extreme temperatures when used at a concentration of 1 mM.

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Arsenobetaine

Arsenobetaine Chemical Structure

CAS No. : 64436-13-1

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Description

Arsenobetaine is an organoarsenical and a compatible solute that has been found in various marine animals, such as lobsters and crabs, as well as terrestrial organisms, including earthworms and lichens. Arsenobetaine is protective against B. subtilis cell death induced by high osmolarity or extreme temperatures when used at a concentration of 1 mM[1][2].

Molecular Weight

178.06

Formula

C5H11AsO2

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

O=C(C[As+](C)(C)C)[O-]

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : 75 mg/mL (421.21 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.6161 mL 28.0804 mL 56.1608 mL
5 mM 1.1232 mL 5.6161 mL 11.2322 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
×
Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 5.6161 mL 28.0804 mL 56.1608 mL 140.4021 mL
5 mM 1.1232 mL 5.6161 mL 11.2322 mL 28.0804 mL
10 mM 0.5616 mL 2.8080 mL 5.6161 mL 14.0402 mL
15 mM 0.3744 mL 1.8720 mL 3.7441 mL 9.3601 mL
20 mM 0.2808 mL 1.4040 mL 2.8080 mL 7.0201 mL
25 mM 0.2246 mL 1.1232 mL 2.2464 mL 5.6161 mL
30 mM 0.1872 mL 0.9360 mL 1.8720 mL 4.6801 mL
40 mM 0.1404 mL 0.7020 mL 1.4040 mL 3.5101 mL
50 mM 0.1123 mL 0.5616 mL 1.1232 mL 2.8080 mL
60 mM 0.0936 mL 0.4680 mL 0.9360 mL 2.3400 mL
80 mM 0.0702 mL 0.3510 mL 0.7020 mL 1.7550 mL
100 mM 0.0562 mL 0.2808 mL 0.5616 mL 1.4040 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Arsenobetaine Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Arsenobetaine
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