AS2690168 (freebase)
AS2690168 freebase is an orally active RANKL signal transduction inhibitor which suppresses RANKL-induced osteoclastogenesis of RAW264 cells. AS2690168 can be utilized in research related to pathological osteolysis.
For research use only. We do not sell to patients.
- CAS No.: 1393999-78-4
- Formula: C17H13F3N4O
- Molecular Weight:346.31
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
0.1 μM
Compound: 22
|
Antiosteoclastogenesis activity in RANKL-stimulated mouse RAW264.7 cells after 3 days by TRAP staining method
Antiosteoclastogenesis activity in RANKL-stimulated mouse RAW264.7 cells after 3 days by TRAP staining method
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[PMID: 22853997] |
Chemical Information
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CAS No. 1393999-78-4
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Molecular Weight 346.31
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Formula C17H13F3N4O
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SMILES
FC1=CC(F)=C(CNC2=C(OC)C=NC(C3=NC=CC=C3)=N2)C(F)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
AS2690168 (freebase) Related Classifications
HY-169857 Related Classifications
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