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Emfizatamab

(Synonyms: GNC-038)
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Based on 1 Customer Validation

Emfizatamab (GNC-038) is a monoclonal antibody against CD19/CD3E/TNFRSF9/PD-L1. Emfizatamab exhibits antitumor activity, being capable of activating CD3 and 4-1BB signals on T cells, as well as targeting the high expression of CD19 or PD-L1 on tumor cells. Emfizatamab functions as a CD19-specific T cell engager by mediating direct antitumor activity. Emfizatamab can also overcome the inhibition of T cells by PD-L1. Emfizatamab can be used in the research of tumors such as R/R non-Hodgkin lymphoma or acute lymphoblastic leukemia.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

  • Reinheit: 95.495%
  • CAS. Nr.: 2559704-23-1
  • Molecular Weight:303.229 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Emfizatamab
  • Experimental Validation Results for Emfizatamab
  • Experimental Validation Results for Emfizatamab
  • Experimental Validation Results for Emfizatamab
  • Experimental Validation Results for Emfizatamab
  • Emfizatamab Chemical Structure
    Emfizatamab Chemical Structure
CAS. Nr.: 2559704-23-1
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Emfizatamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    (scFv-kappa-heavy)-G1_L-kappa-(scFv-heavy-kappa)-(scFv-heavy-kappa)

  • 1/16

    Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Emfizatamab. The EC50 for this effect is 27.4 ng/mL.

  • 1/16

    Immobilized CD19 Protein, Human (HEK293, His, HY-P74330) can bind Emfizatamab. The EC50 for this effect is 57.29 ng/mL.

  • 1/16

    Immobilized 4-1BB/TNFRSF9 Protein, Human, HY-P7125) can bind Emfizatamab. The EC50 for this effect is 1.358 ng/mL.

  • 1/16

    Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Emfizatamab. The EC50 for this effect is 64.84 ng/mL.

  • Emfizatamab Chemical Structure
    1/16
  • Emfizatamab
  • Immobilized CD3 epsilon Protein, Human (HEK293, His, HY-P70506) can bind Emfizatamab. The EC50 for this effect is 27.4 ng/mL.
  • Immobilized CD19 Protein, Human (HEK293, His, HY-P74330) can bind Emfizatamab. The EC50 for this effect is 57.29 ng/mL.
  • Immobilized 4-1BB/TNFRSF9 Protein, Human, HY-P7125) can bind Emfizatamab. The EC50 for this effect is 1.358 ng/mL.
  • Immobilized PD-L1 Protein, Human (HEK293, HY-P73361) can bind Emfizatamab. The EC50 for this effect is 64.84 ng/mL.
  • (scFv-kappa-heavy)-G1_L-kappa-(scFv-heavy-kappa)-(scFv-heavy-kappa)