JNK-IN-13
Based on 1 Customer Validation
JNK-IN-13 (compound 1) is a potent and selective JNK inhibitor with IC50s of 290 nM and 500 nM for JNK3 and JNK2, respectively.
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- Reinheit : 97.60%
- CAS. Nr.: 345986-38-1
- Formel: C13H7ClN4S
- Molecular Weight:286.74
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Speicherung:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
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Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
JNK2 500 nM (IC50) |
JNK3 290 nM (IC50) |
Chemical Information
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CAS. Nr. 345986-38-1
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Appearance Solid
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Molecular Weight 286.74
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Formel C13H7ClN4S
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Color White to yellow
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SMILES
ClC1=NC(C(C2=NC3=CC=CC=C3S2)C#N)=CC=N1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : ≥ 31 mg/mL (108.11 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4875 mL | 17.4374 mL | 34.8748 mL | 87.1870 mL |
| 5 mM | 0.6975 mL | 3.4875 mL | 6.9750 mL | 17.4374 mL | |
| 10 mM | 0.3487 mL | 1.7437 mL | 3.4875 mL | 8.7187 mL | |
| 15 mM | 0.2325 mL | 1.1625 mL | 2.3250 mL | 5.8125 mL | |
| 20 mM | 0.1744 mL | 0.8719 mL | 1.7437 mL | 4.3594 mL | |
| 25 mM | 0.1395 mL | 0.6975 mL | 1.3950 mL | 3.4875 mL | |
| 30 mM | 0.1162 mL | 0.5812 mL | 1.1625 mL | 2.9062 mL | |
| 40 mM | 0.0872 mL | 0.4359 mL | 0.8719 mL | 2.1797 mL | |
| 50 mM | 0.0697 mL | 0.3487 mL | 0.6975 mL | 1.7437 mL | |
| 60 mM | 0.0581 mL | 0.2906 mL | 0.5812 mL | 1.4531 mL | |
| 80 mM | 0.0436 mL | 0.2180 mL | 0.4359 mL | 1.0898 mL | |
| 100 mM | 0.0349 mL | 0.1744 mL | 0.3487 mL | 0.8719 mL |
JNK-IN-13 Related Classifications
HY-77009 Related Classifications
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