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Art. -Nr.: HY-122638

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MRT2000769

MRT2000769 is a Kir7.1 inhibitor with an IC₅₀ of 2 μM. MRT2000769 induces sustained contractions in the uterine muscle of pregnant mice. MRT2000769 is applicable for the research of postpartum hemorrhage.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 1214573-32-6
Formel: C₂₁H₂₆FNO₄
Molecular Weight:375.44

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

MRT2000769 Chemical Structure

CAS. Nr.: 1214573-32-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
- In Vivo
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

Kir7.1

2 μM (IC₅₀)

In Vitro

MRT2000769 (1.1-3.5 μM) potently inhibits recombinant Kir7.1 channels expressed in Chinese hamster ovary cells, with an IC₅₀ of 2 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

MRT2000769 induces persistent contractions in the uterine muscle of mice on gestational day 15.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1214573-32-6
Molecular Weight 375.44
Formel C₂₁H₂₆FNO₄
SMILES

FC1=CC=CC(OC2CCN(CC2)CC(O)C3=CC(OC)=CC=C3OC)=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. McCloskey C, et al. The inwardly rectifying K+ channel KIR7.1 controls uterine excitability throughout pregnancy. EMBO molecular medicine. 2014 Sep;6(9):1161-74. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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