Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

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Art. -Nr.: HY-106477

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Quazinone

(Synonyms: Ro 13-6438; Ro 13-6438/006)

Quazinone is a selective inhibitor of cGMP-inhibited-phosphodiesterase (cGI-PDE, PDE3). Quazinone inhibits the phosphorylation of p42/p44 MAP kinase. Quazinone possesses antimitogenic effect .

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Reinheit: 99.7%

CAS. Nr.: 70018-51-8

Formel: C₁₁H₁₀ClN₃O

Molecular Weight:235.67

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month

Data Sheet (269 KB)

SDS

COA

Quazinone Chemical Structure

CAS. Nr.: 70018-51-8

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Data Download

Data Sheet (269 KB)

SDS

COA

Handling Instructions (2659 KB)

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Finden Sie Ihren Händler vor Ort Your local distributor: Hycultec GmbHHycultec

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Library

High-Throughput Bioactive Compound Library

HY-L205

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen
More

PDE1

PDE2

PDE3

PDE4

PDE5

PDE6

PDE7

PDE9

PDE10

PDE11

PDE12

PDE8

Autotaxin

Biologische Aktivität

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Bioz

Biologische Aktivität

Beschreibung

Quazinone is a selective inhibitor of cGMP-inhibited-phosphodiesterase (cGI-PDE, PDE3). Quazinone inhibits the phosphorylation of p42/p44 MAP kinase. Quazinone possesses antimitogenic effect ^[1].

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen :

PDE1

PDE2

PDE3

PDE4

PDE5

PDE6

PDE7

PDE9

PDE10

PDE11

PDE12

PDE8

Autotaxin

Chemical Information

CAS. Nr. 70018-51-8

Appearance Solid

Molecular Weight 235.67

Formel C₁₁H₁₀ClN₃O

Color White to off-white

SMILES

C[C@H]1N2C(NC3=CC=CC(Cl)=C3C2)=NC1=O

Synonyms

Ro 13-6438; Ro 13-6438/006

Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder -20°C 3 years

4°C 2 years

In solvent -80°C 6 months

-20°C 1 month

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)

SDS (393 KB)

English - EN (393 KB)

Français - FR (393 KB)

Deutsch - DE (393 KB)

Norwegian - NO (393 KB)

Español - ES (393 KB)

Swedish - SV (393 KB)

Italian - IT (393 KB)

Korean - KR (393 KB)

Portuguese - PT (393 KB)

COA (2659 KB)

Elemental Analysis Report (2659 KB)

HNMR (2659 KB)

CNMR (2659 KB)

RP-HPLC (2659 KB)

NP-HPLC (2659 KB)

MS (2659 KB)

LCMS (2659 KB)

IR (2659 KB)

GC (2659 KB)

OR (2659 KB)

SDS-PAGE (2659 KB)

SEC-HPLC (2659 KB)

Other Report (2659 KB)

Handling Instructions (2659 KB)

Verweise

[1]. A Taher, et al. Characterization of cyclic nucleotide phosphodiesterase isoenzymes in the human ureter and their functional role in vitro. World J Urol. 1994;12(5):286-91. [Content Brief]

[2]. M T Osinski, et al. Inhibition of platelet-derived growth factor-induced mitogenesis by phosphodiesterase 3 inhibitors: role of protein kinase A in vascular smooth muscle cell mitogenesis. Biochem Pharmacol. 2000 Aug 1;60(3):381-7. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

=
Konzentration Konzentration

×
Volumen Volumen

×
Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

×

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

=

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

×

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Quazinone Related Classifications

HY-106477 Related Classifications

Metabolic Enzyme/Protease MAPK/ERK Pathway

Phosphodiesterase (PDE) MAPKAPK2 (MK2)

Disease Areas

Infection

Infection

Powered by Bioz See more details on Bioz

Keywords

Quazinone
70018-51-8
Ro 13-6438
Ro 13-6438/006
Phosphodiesterase (PDE)
MAPKAPK2 (MK2)
cGI-PDE
MAP
antimitogenic
Inhibitor
inhibitor
inhibit

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