TLP-3
TLP-3, Temporin L (HY-P2523) analogue, is a SARS-CoV-2 main protease (Mpro) inhibitor with an IC50 of 7.0 μM. TLP-3 inhibits protease activity through stabilizing hydrogen bonding and hydrophobic interactions with key enzyme residues. TLP-3 can be used for the research of ARS-CoV‑2 infection.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C83H110N20O17
- Molecular Weight:1659.89
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
TLP-3 stabilizes SARS-CoV-2 Mpro via favorable domain arrangement and forms strong hydrogen bond interactions with critical Mpro residues[1].
TLP-3 inhibits SARS-CoV-2 Mpro with an IC50 of 7.0 ± 1.5 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 1659.89
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Formel C83H110N20O17
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Sequence
Ser-Ala-Phe-Trp-Gln-Trp-Phe-Ser-Lys-Phe-Leu-Gly-Arg
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Sequence Shortening
SAFWQWFSKFLGR
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)