TYK2 ligand 2
TYK2 ligand 2 is a PROTAC target protein ligand that targets TYK2 and can be used for PROTAC synthesis-related research, such as PROTAC TYD-68 (HY-173357).
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 2924460-80-8
- Formel: C24H20FN7O4
- Molecular Weight:489.46
-
Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
Biologische Aktivität
Beschreibung
IC50 & Target
[1]|
Tyk2 |
In Vitro
TYK2 ligand 2 can serve as a target protein ligand for TYD-68 (HY-173357). TYD-68 is a TYK2 PROTAC degrader that recruits CRBNs, with a DC50 of 0.42 nM, and is selective for JAK1/JAK2-dependent signaling pathways. TYD-68 can inhibit TYK2-mediated signal transduction, downregulate TYK2 protein expression levels, and reduce the secretion of pro-inflammatory factors[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS. Nr. 2924460-80-8
-
Molecular Weight 489.46
-
Formel C24H20FN7O4
-
SMILES
COC1=C(C=CC=C1C2=NC=C(C=N2)F)NC3=CC(NC4=CC=C(C=N4)C(O)=O)=NC=C3C(NC)=O
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
TYK2 ligand 2 Related Classifications
HY-173359 Related Classifications
Powered by Bioz