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Cat. No.: HY-146709

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BET bromodomain inhibitor 2

BET bromodomain inhibitor 2 is a potent BET bromodomain inhibitor with an IC₅₀ of 14.1 µM.

For research use only. We do not sell to patients.

CAS No.: 2414195-69-8
Formula: C₂₃H₃₀N₂O₅S
Molecular Weight:446.56

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (273 KB)

BET bromodomain inhibitor 2 Chemical Structure

CAS No.: 2414195-69-8

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

BET bromodomain inhibitor 2 is a potent BET bromodomain inhibitor with an IC₅₀ of 14.1 µM^[1].

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Chemical Information

CAS No. 2414195-69-8
Molecular Weight 446.56
Formula C₂₃H₃₀N₂O₅S
SMILES

CCN(S(=O)(C1=CC=C(C(C2=CC(OC)=C(C=C2)OC)=C1)[C@H]3CC(N(C3)C)=O)=O)CC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (273 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. J P Hilton-Proctor, et al. Substituted 1-methyl-4-phenylpyrrolidin-2-ones - Fragment-based design of N-methylpyrrolidone-derived bromodomain inhibitors. Eur J Med Chem. 2020 Apr 1;191:112120. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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BET bromodomain inhibitor 2

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