Arachidonate 12-lipoxygenase, 12R-type
Definition:
References:
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[1]. Ignacio Garcia-Verdugo, et al. A role for 12R-lipoxygenase in MUC5AC expression by respiratory epithelial cells. Eur Respir J. 2012 Sep;40(3):714-23. [Content Brief]
[2]. W E Boeglin, et al. A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression. Proc Natl Acad Sci U S A. 1998 Jun 9;95(12):6744-9. [Content Brief]
[3]. D Sun, et al. Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment. J Biol Chem. 1998 Dec 11;273(50):33540-7. [Content Brief]
[4]. Yuxiang Zheng, et al. Lipoxygenases mediate the effect of essential fatty acid in skin barrier formation: a proposed role in releasing omega-hydroxyceramide for construction of the corneocyte lipid envelope. J Biol Chem. 2011 Jul 8;286(27):24046-56. [Content Brief]
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