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BC1 cell line

Definition:

BC1 cell line is a human B-cell-derived cancer cell line derived from Ascites and associated with Primary effusion lymphoma. BC1 cell line is immortalized or transformed by Epstein-Barr virus (EBV). BC1 cell line is used as an in vitro model of Primary effusion lymphoma to investigate tumor-cell growth, cell survival, and pharmacological response.

References:

[1]. Cesarman E, et al. In vitro establishment and characterization of two acquired immunodeficiency syndrome-related lymphoma cell lines (BC-1 and BC-2) containing Kaposi's sarcoma-associated herpesvirus-like (KSHV) DNA sequences. Blood. 1995;86(7):2708-14.

[2]. Moore PS, et al. Primary characterization of a herpesvirus agent associated with Kaposi's sarcomae. Journal of virology. 1996;70(1):549-58.

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