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Ca-Ski

Definition:

Ca-Ski is a human cancer cell line derived from Small intestine and associated with Human papillomavirus-related cervical squamous cell carcinoma and Squamous cell carcinoma of the cervix uteri. Ca-Ski is immortalized or transformed by Human papillomavirus type 16 (HPV16). Ca-Ski is used as an in vitro model of Human papillomavirus-related cervical squamous cell carcinoma and Squamous cell carcinoma of the cervix uteri to investigate apoptosis, cell proliferation, mitochondrial function, and gene-expression regulation.

References:

[1]. Arslan S, et al. Small extracellular vesicle-mediated transfer of HPV16 transcripts from Ca Ski cells increases proliferation of HPV-negative recipient cancer cells. Cell communication and signaling : CCS. 2026;24(1).

[2]. Pei SN, et al. Luteolin (LUT) Induces Apoptosis and Regulates Mitochondrial Membrane Potential to Inhibit Cell Growth in Human Cervical Epidermoid Carcinoma Cells (Ca Ski). Biomedicines. 2024;12(10).

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