Cellular communication network factor 6

Definition:

Plays a role in mitochondrial electron transport and mitochondrial respiration. Through its regulation of the mitochondrial function may play a role in normal postnatal skeletal growth and cartilage homeostasis.

References:

[1]. Milan Patra, et al. CCN6 regulates mitochondrial function. J Cell Sci. 2016 Jul 15;129(14):2841-51. [Content Brief]

[2]. J R Hurvitz, et al. Mutations in the CCN gene family member WISP3 cause progressive pseudorheumatoid dysplasia. Nat Genet. 1999 Sep;23(1):94-8. [Content Brief]

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