CEM-SS

Definition:

CEM-SS is a human T-cell-derived cancer cell line derived from Peripheral blood and associated with Childhood T acute lymphoblastic leukemia and Precursor T-cell acute lymphoblastic leukemia. Its continuous tumor-cell growth supports reproducible mechanistic and pharmacological experiments. CEM-SS is used as an in vitro model of Childhood T acute lymphoblastic leukemia and Precursor T-cell acute lymphoblastic leukemia to investigate endoplasmic-reticulum organization, receptor signaling and trafficking, and cytotoxicity.

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